Clinical Study

Efficacy and Outcomes of Intrathecal Analgesia as Part of an Enhanced Recovery Pathway in Colon and Rectal Surgical Patients

Table 3

Comparison of opioid dosing regimens.

<50 mcg ()51–75 mcg ()76–100 mcg ()>100 mcg () value

Type of intrathecal, (%)0.38
 IA-O20 (100)34 (94)388 (91)105 (89)
 IA-L0 (0)2 (6)39 (9)13 (11)
Incidence of ileus, (%)5 (25)2 (5.6)70 (16)18 (15)0.24
Length of stay (days), median (IQR)4 (2–5.5)3 (2–4.5)3 (2–5)3 (2–5)0.58
Pain score, median (IQR)
 4 hours2 (0.5–3)3 (1–4)3 (2–5)3 (1–4)0.30
 8 hours2 (0–3)2 (1–3)2 (1–4)2 (1–4)0.76
 16 hours3.5 (2–5)3 (2–5)3 (2–5)2 (1–5)0.42
 24 hours3 (1–4)2.5 (2–4.5)4 (2–5)3 (2–6)0.25
 48 hours2 (1–3)3 (2–4)3 (2–5)3 (2–6)0.29
 48-hour maximum5 (4–7.5)5 (4–7)6 (4–7)6 (4–8)0.52
Total OME used, median (IQR)7.5 (0–37.5)7.5 (0–48.8)30 (0–90)22.5 (0–82.5)0.01

IA: intrathecal opioid; IA-L: intrathecal opioid + local anesthetic; IQR: interquartile range.