Surgery Research and Practice / 2021 / Article / Tab 4

Research Article

Preoperative Predictors for 90-Day Mortality after Pancreaticoduodenectomy in Patients with Adenocarcinoma of the Ampulla of Vater: A Single-Centre Retrospective Cohort Study

Table 4

Univariate and multivariable analysis for prediction of 90-day severe morbidity (Clavien–Dindo ≥IIIb) after pancreaticoduodenectomy for ampullary adenocarcinoma.

Severe morbidityUnivariateMultivariable
No (n = 80)Yes (n = 21) value valueORCI 95

Age, mean ± SD59 (10.8)62.5 (12.9)0.141φ
Male sex, count (%)35 (43.8)12 (57.1)0.273χ
Body mass index (kg/m2), mean ± SD24.6 (4.2)26.1 (4.7)0.322φ
MELD score, mean ± SD10.4 (3.9)11.8 (4.8)0.584φ
ALBI grade, count (%)0.653χ
ALBI 125 (31.3)5 (23.8)
ALBI 236 (45)10 (47.6)
ALBI 316 (20)6 (28.6)
Undetermined3 (3.7)0
ASA score, count (%)0.479χ
ASA I2 (2.5)0
ASA II60 (75)14 (66.7)
ASA III18 (22.5)7 (33.3)
eGFR <90 mL/min/1.73 m2, count (%)10 (12.5)8 (38.1)0.011χ0.0036.61.923.4
Preoperative RBC transfusion, count (%)22 (27.5)7 (33.3)0.599χ
Preoperative biliary drainage, count (%)23 (28.7)6 (28.6)0.987χ
Haemoglobin in g/L, mean ± SD116.6 (14)116.5 (17.5)0.487φ
Platelet count in 109/L, mean ± SD339.1 (162)300 (90)0.682φ
International Normalized Ratio, mean ± SD1.08 (0.1)1.17 (0.2)0.072φ0.800
Prothrombin time, mean ± SD12.9 (1.7)14.2 (2.2)0.012φ0.0051.51.12.1
Serum total bilirubin in µmol/L, mean ± SD61.7 (78.2)80.1 (100.7)0.741φ
Serum creatinine in µmol/L, mean ± SD56.3 (14.6)66.6 (17.9)0.008χ0.417
Serum glucose in µmol/L, mean ± SD5.5 (1.9)4.9 (0.5)0.074φ0.2450.60.31.4
Serum albumin in g/L, mean ± SD36.3 (6.2)34.7 (7.6)0.361φ

φMann–Whitney U-test; χchi-square or Fisher's exact test; preoperative laboratory values. Variables with a (italics) in the univariate analysis were used for multivariable analysis. Significance was set at (marked in bold).