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Stroke Research and Treatment
Volume 2010, Article ID 415241, 4 pages
http://dx.doi.org/10.4061/2010/415241
Research Article

Life-Long Physical Activity Involvement and the Risk of Ischemic Stroke in Southern China

1School of Public Health, Curtin Health Innovation Research Institute, Curtin University, GPO Box U 1987, Perth, WA 6845, Australia
2National Drug Research Institute, Curtin University, GPO Box U 1987, Perth, WA 6845, Australia

Received 19 August 2010; Revised 6 December 2010; Accepted 23 December 2010

Academic Editor: Bruce Ovbiagele

Copyright © 2010 Andy H. Lee and Wenbin Liang. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A case-control study was conducted in southern China to investigate the relationship between life-long physical activity involvement and the risk of ischemic stroke. Information on life-long physical activity exposure and other lifestyle characteristics was obtained from 374 incident stroke patients and 464 hospital-based controls using a validated and reliable questionnaire. Logistic regression analyses were performed to assess the association between life-long physical activity involvement and the ischemic stroke risk. The control subjects reported more involvement in physical activity over the life course than the stroke patients ( 𝑃 < . 0 0 1 ). The risk of ischemic stroke was inversely associated with life-long physical activity exposure, with adjusted odds ratio 0.39 (95% confidence interval 0.25 to 0.59) for participants who had always been involved relative to those who have never been much involved. The dose-response relationship was also significant ( 𝑃 < . 0 0 1 ). Therefore, being active life long should be encouraged to prevent this major chronic disease.