Research Article

Factor VII Activating Protease Polymorphism (G534E) Is Associated with Increased Risk for Stroke and Mortality

Table 1

Baseline characteristics of the PROSPER and the GENDER study in patients with Marburg I genotype.

PROSPERGENDER
𝑛 = 5 6 9 7

Continuous variates (mean, SD)
 Age (years)75.3 (3.4)62.1 (10.7)
 Body mass index (kg/m2)26.8 (4.2)27.0 (3.9)
Categorical variates ( 𝑛 , %)
 Male sex2752 (48)2110 (71)
 Current smoker1529 (27)730 (25)
 History of diabetes602 (11)434 (15)
 History of hypertension3530 (62)1189 (40)
 History of myocardial infarction764 (13)1176 (40)
 History of stable angina1529 (27)1977 (67)
Genotype, minor allele frequency (%)
 Marburg I G/A54
 Marburg II G/C*22

All data are presented in number (%) unless otherwise stated.
*In PROSPER and GENDER measured in 5655 and 2959 participants, respectively.