Lentiviral-Mediated shRNA Silencing of PDE4D Gene Inhibits Platelet-Derived Growth Factor-Induced Proliferation and Migration of Rat Aortic Smooth Muscle Cells

Table 1

Information of four designed shRNA and nonsense sequences.

No.	Sequences	Locates	GC %
1	GCGATTATGACCTCTCTCC	181	52.60
2	CCAACCATCCATCAACAAA	368	42.10
3	CCCATGTGCAACCAACCAT	357	52.60
4	CCGGATAATGGAGGAGTTC	1499	52.60
nonsense	TTCTCCGAACGTGTCACGT	—	52.63

The no.  1 locating at 181 achieved the best interfering effect around 72%.