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Stroke Research and Treatment
Volume 2011 (2011), Article ID 690506, 6 pages
Research Article

A Comparison of Cooling Techniques to Treat Cardiac Arrest Patients with Hypothermia

1Stanford Neurocritical Care Program, Stanford Stroke Center, Stanford University School of Medicine Center, Palo Alto, CA 94304, USA
2Stroke Washington Hospital Center, Washington, DC 20010, USA
3Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
4Department of Neurology, NorthShore University Health System, The University of Chicago, Evanston, IL 60201, USA

Received 17 December 2010; Accepted 24 March 2011

Academic Editor: Thomas M. Hemmen

Copyright © 2011 Anna Finley Caulfield et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Introduction. We sought to compare the performance of endovascular cooling to conventional surface cooling after cardiac arrest. Methods. Patients in coma following cardiopulmonary resuscitation were cooled with an endovascular cooling catheter or with ice bags and cold-water-circulating cooling blankets to a target temperature of 32.0–34.0C for 24 hours. Performance of cooling techniques was compared by (1) number of hourly recordings in target temperature range, (2) time elapsed from the written order to initiate cooling and target temperature, and (3) adverse events during the first week. Results. Median time in target temperature range was 19 hours (interquartile range (IQR), 16–20) in the endovascular group versus. 10 hours (IQR, 7–15) in the surface group ( ). Median time to target temperature was 4 (IQR, 2.8–6.2) and 4.5 (IQR, 3–6.5) hours, respectively ( ). Adverse events were similar. Conclusion. Endovascular cooling maintains target temperatures better than conventional surface cooling.