Stroke Research and Treatment / 2011 / Article / Tab 1

Clinical Study

Therapeutic Hypothermia after Cardiac Arrest: Experience at an Academically Affiliated Community-Based Veterans Affairs Medical Center

Table 1

Characteristics of cardiac arrests in which patient survived.

Not in coma after arrest ( 𝑛 = 5 1 arrests, 42 patients)In coma after arrest, not cooled ( 𝑛 = 1 8 arrests, 17 patients)In coma after arrest, cooling started ( 𝑛 = 1 1 arrests, 11 patients)Statistical test for significance

Sex
  Male40 (95)17 (100)10 (91) 𝑃 = 0 . 5 3 e
Age, in yrs 7 0 . 4 ± 1 1 . 1 7 2 . 4 ± 1 2 . 4 6 9 . 5 ± 1 3 . 0 𝐹 = 0 . 2 4 , 𝑃 = 0 . 7 9 f
In-hospital Arrest47 (92)16 (94)11 (100)
Initial cardiac rhythm
 PEA/asystole47 (92)18 (100)10 (91) 𝑃 = 0 . 5 1 e
 VTach/VFib4 (8)0 (0)1 (9)
ROSC in minutes 5 . 2 ± 4 . 6 range (0.1–20)a 3 3 . 5 ± 2 1 . 2 range (5–60)b 2 1 . 9 ± 1 1 . 9 range (5–35)c 𝐹 = 2 9 .6, 𝑃 < 0 . 0 0 1 f
Mechanism of arrest
 1° Cardiac24 (47)4 (22)2 (18) 𝑃 = 0 . 0 7 e
 1° Pulmonary13 (25)8 (44)3 (27) 𝑃 = 0 . 3 3 e
 1° Gastrointestinal1 (2)2 (11)1 (9) 𝑃 = 0 . 1 8 e
 Sepsis/infection5 (10)2 (11)0 (0) 𝑃 = 0 . 7 2 e
 Intraoperative2 (4)2 (11)0 (0) 𝑃 = 0 . 3 0 e
 Unknown/other6 (12)0 (0)5 (45) 𝑃 = 0 . 0 0 5
Comorbidities
 CAD or CHF24 (57)9 (53)7 (64) 𝑃 = 0 . 8 3 e
 Vascular RFs26 (62)13 (76)6 (55) 𝑃 = 0 . 4 7 e
 Cancer8 (19)5 (29)3 (27) 𝑃 = 0 . 6 6 e
 Pulmonary disease8 (19)3 (18)1 (9) 𝑃 = 0 . 9 1 e
 GI/liver5 (12)2 (12)1 (9) 𝑃 = 1 . 0 e
 ESRD6 (14)3 (18)0 (0) 𝑃 = 0 . 4 1 e
 HIV, hepatitis3 (7)1 (6)0 (0) 𝑃 = 1 . 0 e
 Substance abused3 (7)1 (6)2 (18) 𝑃 = 0 . 4 8 e
Expired before discharge13 (31)16 (94)6 (55) 𝑃 < 0 . 0 0 1 e
CPC at discharge
 Favorable (1-2)27 (64)1 (6)5 (45) 𝑃 < 0 . 0 0 1 e
 Unfavorable (3–5)15 (36)16 (94)6 (55)
CPC at 6 Months
 Favorable (1-2)19 (45)0 (0)3 (27) 𝑃 = 0 . 0 0 1 e
 Unfavorable (3–5)23 (55)17 (100)8 (73)

Values as whole number and (percentage), except in case of continuous variable, given as mean ± standard deviation.
ROSC: return of spontaneous circulation; 1°: primary; VTach, ventricular tachycardia; VFib: ventricular fibrillation; vascular RFs: cardiovascular risk factors.
Values as whole number and (percentage), except in case of continuous variable, given as mean ± standard deviation.
aData available for 34 of 51 arrests; bavailable for 10 of 18 arrests; cavailable for 8 of 11 arrests; dsubstance abuse includes alcohol abuse; eFisher’s exact test; fanalysis of variance (ANOVA).

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