Clinical Study

Therapeutic Hypothermia after Cardiac Arrest: Experience at an Academically Affiliated Community-Based Veterans Affairs Medical Center

Table 2

Comatose survivors of cardiac arrest that were treated with therapeutic hypothermia.

Patient no.Date of arrestAgeMechanism of arrestDuration pulselessTime to initiationTime to 33°CTime cooledLowest temp.Rewarming timeComments/CPC at discharge

111/22/200755Suicide attempt, hanging35 mins3.5 hrs11 hrs24 hrsN/A16 hrsAt 72 hrs, intact brainstem reflexes but persistent coma, care withdrawn (CPC 5)
21/26/200883Unknown20 minsCooling stopped when goals of care changed after family arrived; died next day (CPC 5)
35/2/200859Variceal bleeding, aspiration20 minsCooling stopped due to coagulopathy and severe GI bleeding; died next day (CPC 5)
45/27/200885Aspiration30 mins6 hrs9 hrs24 hrs32.1°C12 hrsNeurology called late due to concern for coagulopathy; persistent coma at 72 hrs; care withdrawn a week later (CPC 5)
57/27/200883Cardiac Arrhythmia35 mins2 hrs6 hrs23 hrs31.3°C24 hrsDischarged to rehab unit with short-term memory deficits, required assistance with walking (CPC 2); later diagnosed with gastric cancer, deceased 8 months later
68/20/200861Pericardial tamponadeN/A4 hrs9 hrs24 hrs32.4°C9 hrsInitially treated in OR for tamponade; at 72 hrs in persistent coma with myoclonic status epilepticus; ethics consult called and care withdrawn (CPC 5)
72/21/200957Hyperkalemia, postextubationN/A4 hrs6 hrs22 hrs33.0°C10 hrsAt 72 hr exam, neurologically normal examination; discharged to rehab. unit, still alive and neurologically intact (CPC 1)
82/24/200985Possible vagal hyperactivity5 mins2.5 hrs3 hrs24 hrs32.3°C14 hrsAt 72 hrs, awake and alert, neurologically intact aside from mild confusion (CPC 2); had another arrest 3 weeks later and died
95/29/200959Pulmonary embolus, sepsis5 mins0.5 hrs4 hrs5 hrsN/ACooling stopped due to persistent hypotension and multiorgan failure; deceased two days later (CPC 5)
102/20/201078COPD, aspirationN/A5 hrs9 hrs24 hrs30.5°C22 hrsAt 96 hrs, alert, briskly following commands; remained ventilator dependent, transferred to rehab. unit (CPC 2); died 6 months later
118/10/201059Unknown25 mins2.5 hrs17 hrs24 hrs32.0°C4 hrsMyoclonus while cooled; rewarming occurred quickly and febrile afterwards; despite normal neuroexamination at 72 hrs; discharged to home, still alive (CPC 1)