Stroke Research and Treatment / 2012 / Article / Tab 1

Clinical Study

Previous Leisure-Time Physical Activity Dose Dependently Decreases Ischemic Stroke Severity

Table 1

Main characteristics according to physical activity status before stroke.

Previous physical activity
Yes No OR95% CIP

Demographic characteristics
Age*56 (16–86)73 (25–97)1.621.05–2.50<0.0001
Men71 (53.8%)96 (41.7%)0.027

Medical history
Arterial hypertension56 (42.4%)161 (70.0%)0.320.20–0.49<0.0001
Diabetes23 (17.4%)65 (28.3%)0.540.31–0.910.022
Smoking47 (35.6%)55 (23.9%)1.761.10–2.810.017
Ischemic heart disease15 (11.4%)46 (20.0%)0.510.27–0.960.041
Congestive heart disease6 (4.5%)40 (17.4%)0.230.09–0.55<0.0001
Peripheral arteriopathy4 (3.0%)20 (8.7 %)0.330.11–0.990.047

Previous treatment
Antiplatelet therapy35 (26.5%)88 (38.3%)0.580.36–0.930.028
ACE inhibitors21 (15.9%)63 (27.4%)0.500.29–0.870.014
Angiotensin receptor antagonists9 (6.8%)35 (15.2%)0.410.19–0.880.019
Diuretic26 (19.7%)80 (34.8%)0.460.28–0.770.003
Nitrate derivatives4 (3.0%)27 (11.7%)0.230.08–0.690.003
Digoxin3 (2.3%)24 (10.4%)0.200.06–0.680.003
Other antiarrhythmic drugs4 (3.0%)25 (10.9%)0.260.09–0.760.008

Index stroke0.273
Cerebral infarction102 (77.3%)189 (82.8%)0.740.43–1.25
TIA30 (29.4%)41 (17.8%)1.360.80–2.31

Stroke etiology0.001
Atherosclerosis disease19 (14.4%)54 (23.5%)0.550.31–0.97
Cardioembolic stroke21 (15.9%)65 (28.3%)0.480.28–0.83
Lacunar stroke22 (16.7%)30 (13.0%)1.330.73–2.43
Cervical artery dissection15 (11.4%)7 (3.0%)4.081.61–10.33
Undetermined etiology54 (40.9%)74 (32.2%)1.460.93–2.28

Stroke severity and outcome
NIHSS at admission*3 (0–27)5 (0–35)0.002
Minor stroke (NIHSS 0–3 at admission)72 (54.5%)83 (36.1%)2.131.37–3.290.001
Barthel 95–100 at 8 days100 (75.8%)72 (31.3%)3.592.23–5.79<0.0001
Rankin 0-1 at 8 days76 (57.6%)96 (41.7%)1.891.23–2.930.003
Mini mental state27 (5)24 (10)0.003

Physiological parameters
Systolic Blood Pressure (mm Hg)142 (27)151 (30)0.003
Fibrinogen (μmol/L)10.41 (2.70)11.70 (3.27)<0.0001
Glycemia (mmol/L)5.94 (1.83)6.55 (2.55)0.017
Total cholesterol (mmol/L)5.03 (1.01)5.39 (1.26)0.005
LDL cholesterol (mmol/L)2.89 (0.85)3.17 (1.03)0.005

OR: odds ratio; CI: confidence interval; ACE: angiotensin converting enzyme. *Result is reported as median (range). Result is reported as mean (SD) in patients for whom the test was assessable. All results are given as mean (SD). All other variables did not differ between both groups.