TY - JOUR A2 - Naess, Halvor AU - Szyszkowicz, Mieczysław AU - Porada, Eugeniusz AU - Tremblay, Neil AU - Grafstein, Eric PY - 2012 DA - 2012/03/18 TI - Sulfur Dioxide and Emergency Department Visits for Stroke and Seizure SP - 824724 VL - 2012 AB - The purpose of this study was to assess an association between ambient sulfur dioxide and the number of emergency department (ED) visits for ischemic stroke and seizure. The study used data collected in a Vancouver (Canada) hospital in the years 1999–2003. Daily ED visits diagnosed as ministroke, stroke, or seizure were investigated using the case-crossover technique. Conditional logistic regression models were applied to estimate the odds ratios (ORs) and their respective 95% confidence intervals (CIs). The models included temperature and relative humidity in the form of natural splines. The results were reported for an increase in interquartile range ((IQR), IQR=1.9 ppb for SO2). Positive and statistically significant associations were obtained for SO2 and ischemic stroke for all patients (OR=1.12; CI 1.02, 1.23; lag 3) and for female patients (OR=1.17; CI 1.01, 1.33; lag 0). In the case of ED visits for seizure, for female patients the results were also statistically significant (OR=1.15; CI 1.02, 1.28; lag 1 and OR=1.18; CI 1.05, 1.32; lag 2). These findings suggest that cases of ischemic cerebrovascular accidents are associated with acute exposure to ambient sulfur dioxide. SN - 2090-8105 UR - https://doi.org/10.1155/2012/824724 DO - 10.1155/2012/824724 JF - Stroke Research and Treatment PB - Hindawi Publishing Corporation KW - ER -