Fibrinolytic Activity and Platelet Function in Subjects with Obstructive Sleep Apnoea and a Patent Foramen Ovale: Is There an Option for Prevention of Ischaemic Stroke?
Table 2
Changes in fibrinolytic and platelet parameters from evening to morning.
Variable
Control*
OSA*
PFO†
Evening
Morning
Evening
Morning
Evening
Morning
PAI-1: Ag, ng/mL
8 (6–10)
18 (12–24)
15 (10–20)
26 (17–35)
8 (4–13)
27 (9–45)
PAI-1 activity, U/mL
13 (9–16)
16 (12–20)
14 (9–18)
23 (17–29)
21 (17–25)
27 (10–43)
SIPA, %
47 (41–52)
50 (46–53)
52 (47–58)
54 (48–59)
36 (28–43)
44 (33–55)
2,3-dinor-TXB2/2,3-dinor-PGF
1.2 (0.9–1.4)
1.2 (1.0–1.4)
1.6 (1.0–2.2)
1.7 (1.4–2.1)
0.9 (0.5–1.3)
1.1 (0.8–1.5)
Values are means (95% CI). Blood samples were taken at 6 p.m. (evening) and at 6 a.m. (morning).
*Subjects with PFO are included. †Subjects with OSA are included.
