Fibrinolytic Activity and Platelet Function in Subjects with Obstructive Sleep Apnoea and a Patent Foramen Ovale: Is There an Option for Prevention of Ischaemic Stroke?
Table 3
Urinary excretion of thromboxane and prostacyclin in subjects without PFO.
Variable
Control
OSA
Day
Night
Day
Night
11 DH-TXB2, pg/μmol creatinine
24 (8–41)
18 (9–26)
23 (19–28)
24 (16–31)
2,3-dinor-TXB2, pg/μmol creatinine
18 (11–26)
15 (11–19)
16 (12–19)
15 (12–18)
2,3-dinor-PGF, pg/μmol creatinine
15 (10–20)
14 (9–19)
11 (8–14)
9 (6–12)*
2,3-dinor-TXB2/2,3-dinor-PGF
1.2 (0.9–1.5)
1.2 (1.0–1.5)
1.7 (1.0–2.3)
1.8 (1.5–2.1)
* for difference between the subjects with OSA and the controls during night.