Frontal Lobe Atrophy in Depression after Stroke

Table 2

Multivariate logistic model of the clinical and radiological determinants of DAS.

Variable	Odds ratio (95% CI)	𝑃 value
Severe frontal lobe atrophy	2.648 (1.198–5.856)	0.016
History of depression	11.99 (3.953–36.372)	<0.001
MLES	1.925 (1.490–2.487)	<0.001
LSNS	0.943 (0.915–0.972)	<0.001
NIHSS	1.106 (1.032 –1.185)	0.004
Female	2.312 (1.370–3.902)	0.002
MMSE	—	NS
Education	—	NS

𝑅²=0.259.
NIHSS: National Institute of Health Stroke Scale; MMSE: Mini-Mental State Examination; LSNS: Lubben Social Network Scale; MLES: Modified Life Event Scale; NS: nonsignificant.