Role of Matrix Metalloproteinase Activity in the Neurovascular Protective Effects of Angiotensin Antagonism
Figure 1
Effects of candesartan alone and in combination with FeTPPS and GM6001 on nitrotyrosine (NT) at 24 h after MCAO. Candesartan, FeTTPS, and their combination demonstrated reduced NT compared to the saline treated group (). Candesartan alone reduced NT compared to DMSO and GM6001 alone, but the candesartan combination with GM6001 blunted the effect of candesartan. Values are mean ± SEM ().