Research Article

Role of Matrix Metalloproteinase Activity in the Neurovascular Protective Effects of Angiotensin Antagonism

Figure 1

Effects of candesartan alone and in combination with FeTPPS and GM6001 on nitrotyrosine (NT) at 24 h after MCAO. Candesartan, FeTTPS, and their combination demonstrated reduced NT compared to the saline treated group ( ). Candesartan alone reduced NT compared to DMSO and GM6001 alone, but the candesartan combination with GM6001 blunted the effect of candesartan. Values are mean ± SEM ( ).
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