The R18 Polyarginine Peptide Is More Effective Than the TAT-NR2B9c (NA-1) Peptide When Administered 60 Minutes after Permanent Middle Cerebral Artery Occlusion in the Rat

Table 1

Physiological parameters (mean ± SD).

Parameter	Experimental groups
	Vehicle (saline)	R18 (nmol/kg)			TAT-NR2B9c (nmol/kg)
		100	300	1000	100	300	1000
PaO2, before MCAO	117.19 ± 22.44	114.66 ± 11.34	115.16 ± 13.79	124.16 ± 14.35	109.33 ± 9.04	117.83 ± 16.55	112.83 ± 12.93
PaCO2, before MCAO	38.33 ± 2.94	39 ± 3.57	39.5 ± 3.50	42.68 ± 6.17	43.66 ± 8.93	39.5 ± 5.78	39.83 ± 3.74
pH, before MCAO	7.36 ± 0.05	7.42 ± 0.09	7.37 ± 0.04	7.44 ± 0.06	7.38 ± 0.04	7.45 ± 0.04	7.39 ± 0.06
Glucose (mmol/L), before MCAO	8.0 ± 1.37	8.15 ± 0.68	7.81 ± 0.96	8.11 ± 1.00	7.21 ± 1.31	7.71 ± 0.81	7.50 ± 1.73
BP (mmHg), average during surgery	87.33 ± 4.17	88.33 ± 7.06	84 ± 5.13	91.6 ± 5.44	91 ± 3.09	83.66 ± 6.34	88 ± 3.68
Temperature (°C), average 2 h after surgery	37.51 ± 0.16	37.37 ± 0.25	37.46 ± 0.29	37.46 ± 0.21	37.43 ± 0.25	37.53 ± 0.17	37.52 ± 0.21