Renal Dysfunction Is an Independent Risk Factor for Poor Outcome in Acute Ischemic Stroke Patients Treated with Intravenous Thrombolysis: A New Cutoff Value
Table 1
Baseline characteristics of patients in the control and low GFR groups.
Baseline characteristics
Control group (GFR ≥ 45 mL/min/1.73 m2) ()
Low GFR group (GFR < 45 mL/min/1.73 m2) ()
p value
Age, years, median (IQR)
67 (56–73)
75 (67–77)
value < 0.001
Male, (%)
210 (60.7)
28 (49.1)
p value = 0.100
Hypertension, (%)
217 (63.5)
42 (80.8)
value = 0.014
SBP, mm Hg, median (IQR)
140 (120–160)
150 (130–170)
value = 0.034
DBP, mm Hg, median (IQR)
80 (80–93)
90 (80–100)
p value = 0.150
Diabetes mellitus, (%)
99 (28.9)
19 (36.5)
p value = 0.266
Atrial fibrillation, (%)
99 (29.8)
16 (30.8)
p value = 0.889
Smoking, (%)
117 (34.4)
7 (13.5)
value = 0.002
Hyperlipidemia, (%)
136 (40.2)
16 (30.8)
p value = 0.193
Previous use of antithrombotics, (%)
84 (31.7)
13 (39.4)
p value = 0.374
Previous ischemic stroke, (%)
31 (9.1)
8 (15.4)
p value = 0.160
Glucose, mg/dL, median (IQR)
129 (107–169)
139 (115–170)
p value = 0.390
Stroke severity, NIHSS, median (IQR)
15 (10–18)
16 (11–20)
p value = 0.243
Onset to treatment time, median (IQR)
150 (120–180)
147 (119–171)
p value = 0.466
DBP = diastolic blood pressure; GFR = glomerular filtration rate; IQR = interquartile range; NIHSS = National Institutes of Health Stroke Scale; SBP = systolic blood pressure.
