Remote Assessment of Platelet Function in Patients with Acute Stroke or Transient Ischaemic Attack

Table 4

P-selectin (median fluorescence) in response to ADP and arachidonic acid (AA), by antiplatelet medication taken prior to randomisation, whether before or after stroke/TIA. Data are number (%) or mean (standard deviation). Comparisons by Chi-square test or one-way analysis of variance.

	All	Aspirin	Asp/Dip	Asp/Clop	Clopidogrel	None
AA
Number (%)	656 (21.2)	418 (20.5)	42 (25.6)	33 (15.3)	54 (34.2)	108 (21.1)
Mean (SD)	299 (312)	198 (172)	296 (269)	256 (227)	693 (381)	509 (448)	<0.001
, none versus	—	<0.001	0.002	0.005	<0.001	—	—
<400 (%)	546 (83.2)	398 (95.2)	35 (83.3)	29 (87.9)	15 (27.8)	68 (63)	<0.001
<500 (%)	557 (84.9)	404 (96.7)	37 (88.1)	29 (87.9)	16 (29.6)	70 (64.8)	<0.001
ADP
Number (%)	682 (22)	424 (20.8)	42 (25.6)	50 (23.3)	54 (34.2)	110 (21.4)
Mean (SD)	925 (331)	944 (298)	758 (296)	1139 (388)	578 (276)	983 (316)	<0.001
, none versus	—	0.54	0.10	<0.001	<0.001	—	—
<860 (%) [33]	293 (43)	172 (40.6)	27 (64.3)	11 (22)	45 (83.3)	37 (33.6)	<0.001
<625 (%)	125 (18.3)	55 (13)	15 (35.7)	6 (12)	34 (63)	14 (12.7)	<0.001
<500 (%)	68 (10)	28 (6.6)	6 (14.3)	3 (6)	23 (42.6)	7 (6.4)	<0.001

One patient on triple antiplatelet therapy (ADP 487 IU, AA 161 IU) and one patient on dipyridamole alone (ADP 1562 IU) (protocol violations) are excluded.
Protocol violation [34].