Clinical Study

Longitudinal Study on Low-Dose Aspirin versus Placebo Administration in Silent Brain Infarcts: The Silence Study

Table 6

ANOVARM models on cognitive domains.

ā€‰ā€‰TreatmentVisitTreatmentVisit
p-valuep-valuep-value

Psychomotor speedNon imputed0.17760.36400.0976
LOCF0.25230.68860.6286
Memory performanceNon imputed0.37440.06030.8072
LOCF0.65120.00110.3446
Global cognitive indexNon imputed0.84490.15480.9128
LOCF0.9332<0.00010.8932

General cognitive evaluationNon imputed0.69690.39130.5367
LOCF0.98610.02010.3556
Episodic memoryNon imputed0.90320.34660.6365
LOCF0.49480.09670.3351
Short-term memoryNon imputed0.27310.92640.9663
LOCF0.45430.96300.5808
Executive functionsNon imputed0.81230.62110.5504
LOCF0.09520.86170.4169
LanguageNon imputed0.27120.98910.9413
LOCF0.64220.70700.8942
Problem solvingNon imputed0.73870.70720.3618
LOCF0.84050.02240.0677
Dementia stagingNon imputed0.52260.16990.5337
LOCF0.64450.78730.4778
Daily living activitiesNon imputed0.40630.92330.9826
LOCF0.12880.99790.3036
Major psychiatric disordersNon imputed0.11390.38790.1515
LOCF0.10280.00790.4263