Clinical Study
Longitudinal Study on Low-Dose Aspirin versus Placebo Administration in Silent Brain Infarcts: The Silence Study
Table 6
ANOVARM models on cognitive domains.
| ā | ā | Treatment | Visit | TreatmentVisit | p-value | p-value | p-value |
| Psychomotor speed | Non imputed | 0.1776 | 0.3640 | 0.0976 | LOCF | 0.2523 | 0.6886 | 0.6286 | Memory performance | Non imputed | 0.3744 | 0.0603 | 0.8072 | LOCF | 0.6512 | 0.0011 | 0.3446 | Global cognitive index | Non imputed | 0.8449 | 0.1548 | 0.9128 | LOCF | 0.9332 | <0.0001 | 0.8932 |
| General cognitive evaluation | Non imputed | 0.6969 | 0.3913 | 0.5367 | LOCF | 0.9861 | 0.0201 | 0.3556 | Episodic memory | Non imputed | 0.9032 | 0.3466 | 0.6365 | LOCF | 0.4948 | 0.0967 | 0.3351 | Short-term memory | Non imputed | 0.2731 | 0.9264 | 0.9663 | LOCF | 0.4543 | 0.9630 | 0.5808 | Executive functions | Non imputed | 0.8123 | 0.6211 | 0.5504 | LOCF | 0.0952 | 0.8617 | 0.4169 | Language | Non imputed | 0.2712 | 0.9891 | 0.9413 | LOCF | 0.6422 | 0.7070 | 0.8942 | Problem solving | Non imputed | 0.7387 | 0.7072 | 0.3618 | LOCF | 0.8405 | 0.0224 | 0.0677 | Dementia staging | Non imputed | 0.5226 | 0.1699 | 0.5337 | LOCF | 0.6445 | 0.7873 | 0.4778 | Daily living activities | Non imputed | 0.4063 | 0.9233 | 0.9826 | LOCF | 0.1288 | 0.9979 | 0.3036 | Major psychiatric disorders | Non imputed | 0.1139 | 0.3879 | 0.1515 | LOCF | 0.1028 | 0.0079 | 0.4263 |
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