Cerebral Venous Sinus Thrombosis in Women: Subgroup Analysis of the VENOST Study

Table 1

Compared data of demographic and clinical aspects of groups.

Compared data	RHRF (-)		RHRF (+)
	Age
Years		%		%	<0.001
Mode of onset
Acute	187^a	42	195^b	62
Subacute	150^a	34	82^b	26	<0.001
Chronic	110^a	25	38^b	12
Clinical symptoms and signs
Isolated headache	119	26	66	20	0.057
Headache	387	85	282	87	0.523
Nausea and vomiting	116	26	107	33	0.024
Epileptic seizures	98	22	110	34	<0.001
Visual field defect	131	29	66	20	0.007
Focal neurological deficit	72	16	81	25	0.002
Altered consciousness	78	17	67	21	0.222
Cranial nerve palsies	59	13	24	7	0.012
Radiological work-up
Cranial MRI	23	5	23	7	0.492
Cranial MRV	19	4	12	4
Cranial MRI+MRV	398	88	284	88
Cranial CT+MRV	10	2	4	1
Number of sinuses involved
1 sinus	230	51	143	44	0.281
2 sinuses	148	33	126	39
More than 2 sinuses	75	16	55	17
Involved sinuses
Isolated transverse sinuses	122	27	78	24	0.369
Isolated sagittal sinuses	66	15	44	14	0.697
Isolated sigmoid sinuses	18	4	7	2	0.158
Isolated cortical veins	8	2	11	3	0.147
Isolated jugular sinuses	9	2	1	0	0.052
Isolated cavernous sinuses	6	1	0	0	0.044
Transverse sinuses	329	73	243	75	0.459
Sigmoid sinuses	183	40	127	39	0.736
Sagittal sinuses	157	35	134	41	0.057
Internal jugular vein	71	16	47	15	0.655
Cortical veins	13	3	16	5	0.134
Cavernous sinuses	12	3	3	1	0.085
Parenchymal involvement
No lesion	280^a	62	164^b	51	0.003
Infarction	87^a	19	66^a	20
Hemorrhagic infarction	68^a	15	80^b	25
Intracerebral hemorrhage	18^a	4	14^a	4

MRI: magnetic resonance imaging; MRV: magnetic resonance venography; CT: computed tomography.