Stroke Research and Treatment

Therapeutic Hypothermia in Stroke


Publishing date
01 Jul 2011
Status
Published
Submission deadline
01 Jan 2011

1Department of Neurology, University of California, San Francisco and the San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA

2Department of Psychology, University of Alberta, Edmonton, AB, Canada

3University of California, San Diego, CA, USA

4Department of Physiology, Kyungpook University, Daegu, South Korea

5Department of Neurology, University of Copenhagen, Copenhagen, Denmark


Therapeutic Hypothermia in Stroke

Description

Therapeutic hypothermia is a promising neuroprotective intervention shown to improve outcome from brain ischemia in humans. Ample research indicates that it is a robust protectant in various animal models of acute neurological injury. Translation into clinical practice has only been convincingly demonstrated to improve neurological outcome after cardiac arrest and neonatal hypoxia-ischemia. Applying hypothermia to stroke patients is fraught with logistical and methodological challenges. This issue will focus on the state of therapeutic hypothermia, its applications, its pathophysiological mechanisms of protection, and its potential for future clinical use in stroke. Manuscripts of original research and review topics are welcome.

The topics to be covered include, but are not limited to:

  • Effective cooling methods in patients (endovascular, surface, pharmacological, etc.)
  • Cooling challenges in stroke patients
  • Therapeutic hypothermia in patients with ischemic and hemorrhagic stroke, subarachnoid hemorrhage, and pediatric stroke
  • Prevention of hyperthermia or maintenance of normothermia
  • Molecular and cellular mechanisms underlying hypothermic protection
  • Future strategies for cooling and combination therapy
  • Optimal application of cooling (timing, duration, etc.)

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/srt/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2011
  • - Article ID 157969
  • - Editorial

Therapeutic Hypothermia in Stroke

Midori A. Yenari | Fred Colbourne | ... | Derk Krieger
  • Special Issue
  • - Volume 2011
  • - Article ID 131834
  • - Review Article

Limited Therapeutic Time Windows of Mild-to-Moderate Hypothermia in a Focal Ischemia Model in Rat

Heng Zhao | Gary Steinberg
  • Special Issue
  • - Volume 2011
  • - Article ID 690506
  • - Research Article

A Comparison of Cooling Techniques to Treat Cardiac Arrest Patients with Hypothermia

Anna Finley Caulfield | Shylaja Rachabattula | ... | Christine A. C. Wijman
  • Special Issue
  • - Volume 2011
  • - Article ID 689290
  • - Review Article

Experimental and Clinical Use of Therapeutic Hypothermia for Ischemic Stroke: Opportunities and Limitations

Tine Zgavc | An-Gaëlle Ceulemans | ... | Said Hachimi-Idrissi
  • Special Issue
  • - Volume 2011
  • - Article ID 791639
  • - Clinical Study

Therapeutic Hypothermia after Cardiac Arrest: Experience at an Academically Affiliated Community-Based Veterans Affairs Medical Center

Maulik P. Shah | Leslie Zimmerman | ... | Midori A. Yenari
  • Special Issue
  • - Volume 2011
  • - Article ID 846716
  • - Research Article

Mild Hypothermia Attenuates Intercellular Adhesion Molecule-1 Induction via Activation of Extracellular Signal-Regulated Kinase-1/2 in a Focal Cerebral Ischemia Model

Jung Sook Choi | Jaechan Park | ... | Hyung Soo Han
  • Special Issue
  • - Volume 2011
  • - Article ID 809874
  • - Review Article

Molecular Mechanisms Underlying Hypothermia-Induced Neuroprotection

Yasushi Shintani | Yasuko Terao | Hiroyuki Ohta
Stroke Research and Treatment
 Journal metrics
Acceptance rate24%
Submission to final decision93 days
Acceptance to publication32 days
CiteScore3.400
Impact Factor-
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