Influence of the Generator in-Growth Time on the Final Radiochemical Purity and Stability of ^99mTc Radiopharmaceuticals

Table 5

RCP of radiopharmaceuticals at 𝑡=0 and at the expired time specified by the manufacturer, prepared with the first eluate obtained from DRYTEC GE Healthcare generator.

Commercial name	Radiopharmaceutical	RCP (𝑡=0)	RCPex	RCP requirements
Neurolite	^99mTc-ECD	99.17±0.25	99.13±0.21	≥90%
Cardiolite	^99mTc-Sestamibi	97.67±1.24	97.71±1.13	≥94%
Stamicis	^99mTc-Sestamibi	98.65±0.40	98.57±0.57	≥94%
Technemibi	^99mTc-Sestamibi	98.15±0.11	98.01±0.04	≥94%
TechneScan	^99mTc-MAG3	98.79±0.02	98.11±0.15	≥95%
Pentacis	^99mTc-DTPA	99.03±0.24	99.88±0.11	≥95%
Medronato II	^99mTc-MDP	98.10±0.13	98.02±0.15	≥95%
Osteocis	^99mTc-HMDP	99.23±0.18	98.15±0.16	≥95%
Nanocoll (PRC = 40 min)	^99mTc-nanocolloids	98.22±0.13	98.33±0.39	≥95%
Renocis	^99mTc-DMSA	99.28±0.07	98.55±0.21	≥95%

RCPex indicates the radiochemical purity at the end of the expired time.