Table of Contents
Scholarly Research Exchange
Volume 2009, Article ID 963818, 6 pages
Case Report

Invasive Breast Cancer after Mastectomy and Autologous Breast Reconstruction

1Division of General Surgery, Mayo Clinic, Rochester, MN 55905, USA
2Division of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
3Division of Plastic and Reconstructive Surgery, Mayo Clinic, Rochester, MN 55905, USA

Received 22 July 2008; Accepted 8 February 2009

Copyright © 2009 Shaheen Zakaria et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Recurrence or new breast cancer after mastectomy and autologous breast reconstruction is a rare occurrence. We present a case series of four patients with this rare phenomenon and describe their presentation, workup, and surgical and adjuvant therapy. We discuss the possible physiologic mechanisms leading to tumor recurrence in a reconstructed breast along with literature review. A new palpable mass in a reconstructed breast mound warrants tissue diagnosis to avoid delay in treatment. The surgical options for breast cancer in tissue reconstructions depend on the location and extent of the tumor, involvement of the vascular pedicle, stage of disease, and adjuvant therapy options.