Under- and Normal-Weight Patients Are More Susceptible to Recurrence of Phyllodes Tumor

Table 2

Factors associated with locoregional recurrence of phyllodes tumor.

Variables	No local recurrence	Local recurrence	HR (univariate)	95% CI (univariate)	value	HR (multivariate)	95% CI (multivariate)	value
BMI
<23 kg/m^2	29	14	Ref			Ref
≥23 kg/m^2	48	8	0.405	0.169–0.968	0.042	0.386	0.156–0.954	0.039
OP name
Wide excision	71	21	Ref
Mastectomy	7	1	0.753	0.101–5.635	0.782
Size
<5 cm	54	7	Ref			Ref
≥5 cm	23	15	3.506	1.423–8.637	0.006	2.671	1.066–6.694	0.036
Grade
Benign	52	13	Ref
Borderline	22	7	0.872	0.346–2.197	0.772
Malignant	4	2	1.327	0.298–5.920	0.711
Stromal hypercellularity
Mild	23	7	Ref
Moderate	49	12	0.409	0.152–1.099	0.076
Marked	4	3	1.089	0.277–4.284	0.903
Cellular atypia
Mild	56	14	Ref
Moderate	15	6	1.005	0.384–2.626	0.992
Marked	5	2	1.119	0.252–4.973	0.883
Mitosis
0–4	56	10	Ref
5–9	8	7	2.821	1.060–7.505	0.038
≤10	9	4	1.446	0.452–4.624	0.534
Tumor border
Pushing	11	3	Ref
Infiltrative	65	19	1.232	0.361–4.211	0.739
Stromal overgrowth
No	65	14	Ref
Yes	11	8	2.654	1.086–6.484	0.032	2.706	1.046–6.999	0.040
Resection margin
Negative	57	11	Ref
Positive	20	11	1.873	0.794–4.419	0.152

HR, hazards ratio; CI, confidence interval; BMI, body mass index; OP, operation.