Table of Contents
Thrombosis
Volume 2011 (2011), Article ID 505373, 11 pages
http://dx.doi.org/10.1155/2011/505373
Review Article

Deep Vein Thrombosis Prophylaxis in Trauma Patients

1Orthopaedic Trauma Research, Denver Health, University of Colorado, 777 Bannock Street MC 0188, Denver, CO 80204, USA
2Denver Health, University of Colorado, 777 Bannock Street MC 0188, Denver, CO 80204, USA

Received 1 November 2010; Accepted 10 March 2011

Academic Editor: Omer Iqbal

Copyright © 2011 Serdar Toker et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. E. Raskob, R. Silverstein, D. W. Bratzler, J. A. Heit, and R. H. White, “Surveillance for deep vein thrombosis and pulmonary embolism: recommendations from a national workshop,” American Journal of Preventive Medicine, vol. 38, no. 4, pp. S502–S509, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  2. M. Cushman, “Epidemiology and risk factors for venous thrombosis,” Seminars in Hematology, vol. 44, no. 2, pp. 62–69, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  3. M. M. Knudson, D. G. Ikossi, L. Khaw et al., “Thromboembolism after trauma: an analysis of 1602 episodes from the American College of Surgeons National Trauma Data Bank,” Annals of Surgery, vol. 240, no. 3, pp. 490–498, 2004. View at Publisher · View at Google Scholar
  4. R. W. Eppsteiner, J. J. Shin, J. Johnson, and R. M. Van Dam, “Mechanical compression versus subcutaneous heparin therapy in postoperative and posttrauma patients: a systematic review and meta-analysis,” World Journal of Surgery, vol. 34, no. 1, pp. 10–19, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  5. T. Paffrath, A. Wafaisade, R. Lefering et al., “Venous thromboembolism after severe trauma: incidence, risk factors and outcome,” Injury, vol. 41, no. 1, pp. 97–101, 2010. View at Publisher · View at Google Scholar · View at PubMed
  6. T. C. Chiasson, B. J. Manns, and H. T. Stelfox, “An economic evaluation of venous thromboembolism prophylaxis strategies in critically ill trauma patients at risk of bleeding,” PLoS Medicine, vol. 6, no. 6, Article ID e1000098, 2009. View at Publisher · View at Google Scholar · View at PubMed
  7. D. A. Reiff, R. N. Haricharan, N. M. Bullington, R. L. Griffin, G. McGwin, and L. W. Rue, “Traumatic brain injury is associated with the development of deep vein thrombosis independent of pharmacological prophylaxis,” The Journal of Trauma, vol. 66, no. 5, pp. 1436–1440, 2009. View at Google Scholar · View at Scopus
  8. S. M. Fakhry and C. P. Michetti, “Bleeding and coagulation complications,” in Trauma, E. E. Moore, D. V. Feliciano, and K. L. Mattox, Eds., pp. 1251–1270, McGraw-Hill, 2004. View at Google Scholar
  9. W. H. Geerts, K. I. Code, R. M. Jay, E. Chen, and J. P. Szalai, “A prospective study of venous thromboembolism after major trauma,” New England Journal of Medicine, vol. 331, no. 24, pp. 1601–1606, 1994. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  10. R. Selby, W. Geerts, F. A. Ofosu et al., “Hypercoagulability after trauma: hemostatic changes and relationship to venous thromboembolism,” Thrombosis Research, vol. 124, no. 3, pp. 281–287, 2009. View at Publisher · View at Google Scholar · View at PubMed
  11. K. Brohi, M. J. Cohen, M. T. Ganter et al., “Acute coagulopathy of trauma: hypoperfusion induces systemic anticoagulation and hyperfibrinolysis,” Journal of Trauma, vol. 64, no. 5, pp. 1211–1217, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  12. S. Sevitt and N. Gallagher, “Venous thrombosis and pulmonary embolism. A clinico-pathological study in injured and burned patients,” The British Journal of Surgery, vol. 48, pp. 475–489, 1961. View at Google Scholar
  13. C. Bendinelli and Z. Balogh, “Postinjury thromboprophylaxis,” Current Opinion in Critical Care, vol. 14, no. 6, pp. 673–678, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  14. W. L. Chandler and N. M. Dunbar, “Thrombin generation in trauma patients,” Transfusion, vol. 49, no. 12, pp. 2652–2660, 2009. View at Publisher · View at Google Scholar · View at PubMed
  15. S. R. Shackford, J. W. Davis, P. Hollingsworth-Fridlund, N. S. Brewer, D. B. Hoyt, and R. C. Mackersie, “Venous thromboembolism in patients with major trauma,” American Journal of Surgery, vol. 159, no. 4, pp. 365–369, 1990. View at Google Scholar · View at Scopus
  16. D. J. Hak, “Prevention of venous thromboembolism in trauma and long bone fractures,” Current Opinion in Pulmonary Medicine, vol. 7, no. 5, pp. 338–343, 2001. View at Google Scholar · View at Scopus
  17. K. A. Kudsk, T. C. Fabian, S. Baum, R. E. Gold, E. Mangiante, and G. Voeller, “Silent deep vein thrombosis in immobilized multiple trauma patients,” American Journal of Surgery, vol. 158, no. 6, pp. 515–519, 1989. View at Publisher · View at Google Scholar · View at Scopus
  18. I. Datta, C. G. Ball, L. Rudmik, S. M. Hameed, and J. B. Kortbeek, “Complications related to deep venous thrombosis prophylaxis in trauma: a systematic review of the literature,” Journal of Trauma Management & Outcomes, vol. 4, no. 1, 2010. View at Google Scholar
  19. A. P. Ekeh, K. M. Dominguez, R. J. Markert, and M. C. McCarthy, “Incidence and risk factors for deep venous thrombosis after moderate and severe brain injury,” Journal of Trauma, vol. 68, no. 4, pp. 912–915, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  20. A. J. Ruiz, S. L. Hill, and R. E. Berry, “Heparin, deep venous thrombosis, and trauma patients,” American Journal of Surgery, vol. 162, no. 2, pp. 159–162, 1991. View at Publisher · View at Google Scholar
  21. J.-P. Lu, M. M. Knudson, N. Bir, R. Kallet, and K. Atkinson, “Fondaparinux for prevention of venous thromboembolism in high-risk trauma patients: a pilot study,” Journal of the American College of Surgeons, vol. 209, no. 5, pp. 589–594, 2009. View at Publisher · View at Google Scholar · View at PubMed
  22. M. M. Gearhart, F. A. Luchette, M. C. Proctor et al., “The risk assessment profile score identifies trauma patients at risk for deep veto thrombosis,” Surgery, vol. 128, no. 4, pp. 631–640, 2000. View at Publisher · View at Google Scholar · View at PubMed
  23. T. Sase, H. Wada, Y. Kamikura et al., “Tissue factor messenger RNA levels in leukocytes compared with tissue factor antigens in plasma from patients in hypercoagulable state caused by various diseases,” Thrombosis and Haemostasis, vol. 92, no. 1, pp. 132–139, 2004. View at Google Scholar · View at Scopus
  24. P. C. Spinella, C. L. Carroll, I. Staff et al., “Duration of red blood cell storage is associated with increased incidence of deep vein thrombosis and in hospital mortality in patients with traumatic injuries,” Critical Care, vol. 13, no. 5, p. R151, 2009. View at Google Scholar · View at Scopus
  25. Y. Fujii, E. F. Mammen, A. Farag, J. Muz, G. G. Salciccioli, and S. T. Weingarden, “Thrombosis in spinal cord injury,” Thrombosis Research, vol. 68, no. 4-5, pp. 357–368, 1992. View at Publisher · View at Google Scholar · View at Scopus
  26. G. C. Velmahos, J. Kern, L. S. Chan, D. Oder, J. A. Murray, and P. Shekelle, “Prevention of venous, thromboembolism after injury: an evidence-based report—part II: analysis of risk factors and evaluation of the role of vena caval filters,” Journal of Trauma, vol. 49, no. 1, pp. 140–144, 2000. View at Google Scholar · View at Scopus
  27. P. Myllynen, M. Kammonen, and P. Rokkanen, “Deep venous thrombosis and pulmonary embolism in patients with acute spinal cord injury: a comparison with nonparalyzed patients immobilized due to spinal fractures,” Journal of Trauma, vol. 25, no. 6, pp. 541–543, 1985. View at Google Scholar · View at Scopus
  28. L. J. Greenfield, M. C. Proctor, J. L. Rodriguez, F. A. Luchette, M. D. Cipolle, and J. Cho, “Posttrauma thromboembolism prophylaxis,” Journal of Trauma, vol. 42, no. 1, pp. 100–103, 1997. View at Publisher · View at Google Scholar · View at Scopus
  29. K. Kitagawa and S. Sakoda, “Mechanism underlying thrombus formation in cerebral infarction,” Rinshō Shinkeigaku, vol. 49, no. 11, pp. 798–800, 2009. View at Google Scholar
  30. A. E. Seyfer, A. V. Seaber, F. A. Dombrose, and J. R. Urbaniak, “Coagulation changes in elective surgery and trauma,” Annals of Surgery, vol. 193, no. 2, pp. 210–213, 1981. View at Google Scholar · View at Scopus
  31. J. T. Owings, M. Bagley, R. Gosselin, D. Romac, and E. Disbrow, “Effect of critical injury on plasma antithrombin activity: low antithrombin levels are associated with thromboembolic complications,” Journal of Trauma, vol. 41, no. 3, pp. 396–406, 1996. View at Google Scholar · View at Scopus
  32. S. Attar, D. Boyd, E. Layne, J. McLaughlin, A. R. Mansberger, and R. A. Cowley, “Alterations in coagulation and fibrinolytic mechanisms in acute trauma,” Journal of Trauma, vol. 9, no. 11, pp. 939–965, 1969. View at Google Scholar · View at Scopus
  33. B. L. Enderson, J. P. Chen, R. Robinson, and K. I. Maull, “Fibrinolysis in multisystem trauma patients,” Journal of Trauma, vol. 31, no. 9, pp. 1240–1246, 1991. View at Google Scholar · View at Scopus
  34. K. Okamura, I. Nakagawa, S. Hidaka, Y. Okada, T. Kubo, and T. Kato, “Preoperative hypercoagulopathy in patients undergoing orthopedic lower extremity surgery,” Japanese Journal of Anesthesiology, vol. 57, no. 10, pp. 1207–1212, 2008. View at Google Scholar · View at Scopus
  35. D. Peetz, G. Hafner, M. Hansen et al., “Dose-adjusted thrombosis prophylaxis in trauma surgery according to levels of D-Dimer,” Thrombosis Research, vol. 98, no. 6, pp. 473–483, 2000. View at Publisher · View at Google Scholar · View at Scopus
  36. M. H. Meissner, W. L. Chandler, and J. S. Elliott, “Venous thromboembolism in trauma: a local manifestation of systemic hypercoagulability?” Journal of Trauma, vol. 54, no. 2, pp. 224–231, 2003. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  37. D. T. Engelman, S. G. A. Gabram, L. Allen, G. E. Ens, and L. M. Jacobs, “Hypercoagulability following multiple trauma,” World Journal of Surgery, vol. 20, no. 1, pp. 5–10, 1996. View at Publisher · View at Google Scholar · View at Scopus
  38. D. J. Dries, “Activation of the clotting system and complement after trauma,” New Horizons, vol. 4, no. 2, pp. 276–288, 1996. View at Google Scholar · View at Scopus
  39. K. Brohi, M. J. Cohen, M. T. Ganter et al., “Acute coagulopathy of trauma: hypoperfusion induces systemic anticoagulation and hyperfibrinolysis,” Journal of Trauma, vol. 64, no. 5, pp. 1211–1217, 2008. View at Publisher · View at Google Scholar · View at PubMed
  40. J. B. Toro, M. J. Gardner, C. Hierholzer et al., “Long-term consequences of pelvic trauma patients with thromboembolic disease treated with inferior vena caval filters,” The Journal of trauma, vol. 65, no. 1, pp. 25–29, 2008. View at Google Scholar
  41. A. N. Nicolaides, V. V. Kakkar, E. S. Field, and P. Fish, “Venous stasis and deep-vein thrombosis,” British Journal of Surgery, vol. 59, no. 9, pp. 713–717, 1972. View at Google Scholar
  42. E. C. Rossi, D. Green, and J. S. Rosen, “Sequential changes in factor VIII and platelets preceding deep vein thrombosis in patients with spinal cord injury,” British Journal of Haematology, vol. 45, no. 1, pp. 143–151, 1980. View at Google Scholar
  43. P. Myllynen, M. Kammonen, and P. Rokkanen, “The blood F VIII:Ag/F VIII:C ratio as an early indicator of deep venous thrombosis during post-traumatic immobilization,” Journal of Trauma, vol. 27, no. 3, pp. 287–290, 1987. View at Google Scholar
  44. E. F. Leonard, “Reology of thrombosis,” in Hemostasisi and Thrombosis. Basic Principles and Clinical Practice, R. W. Colman, J. Hirsch, V. J. Marder, and E. W. Salzman, Eds., p. 1111, Lippincott, Philedelphia, Pa, USA, 2nd edition, 1987. View at Google Scholar
  45. W. H. Geerts, J. A. Heit, G. P. Clagett et al., “Prevention of venous thromboembolism,” Chest, vol. 119, no. 1, pp. 132S–175S, 2001. View at Google Scholar
  46. C. C. Cothren, W. R. Smith, E. E. Moore, and S. J. Morgan, “Utility of once-daily dose of low-molecular-weight heparin to prevent venous thromboembolism in multisystem trauma patients,” World Journal of Surgery, vol. 31, no. 1, pp. 98–104, 2007. View at Publisher · View at Google Scholar · View at PubMed
  47. S. E. Matthiasson, B. Lindblad, and D. Bergqvist, “Prevention of experimental venous thrombosis in rabbits with low molecular weight heparin, dextran and their combinations, administered before or during induction of venous endothelial trauma,” Thrombosis Research, vol. 74, no. 6, pp. 655–663, 1994. View at Publisher · View at Google Scholar
  48. C. Venet, C. Berger, B. Tardy, A. Viallon, H. Decousus, and J. C. Bertrand, “Prevention of venous thromboembolism in polytraumatized patients. Epidemiology and importance,” La Presse Médicale, vol. 29, no. 2, pp. 68–75, 2000. View at Google Scholar
  49. D. M. Becker, “Venous thromboembolism: epidemiology, diagnosis, prevention,” Journal of General Internal Medicine, vol. 1, no. 6, pp. 402–411, 1986. View at Google Scholar
  50. F. B. Rogers, M. D. Cipolle, G. Velmahos, G. Rozycki, and F. A. Luchette, “Practice management guidelines for the prevention of venous thromboembolism in trauma patients: the EAST practice management guidelines work group,” Journal of Trauma, vol. 53, no. 1, pp. 142–164, 2002. View at Google Scholar
  51. D. Ganzer, A. Gutezeit, and G. Mayer, “Potentials risks in drug prevention of thrombosis—low-molecular-weight heparin versus standard heparin,” Zeitschrift fur Orthopadie und Ihre Grenzgebiete, vol. 137, no. 5, pp. 457–461, 1999. View at Google Scholar
  52. W. H. Geerts, R. M. Jay, K. I. Code et al., “A comparison of low-dose heparin with low-molecular-weight heparin as prophylaxis against venous thromboembolism after major trauma,” New England Journal of Medicine, vol. 335, no. 10, pp. 701–707, 1996. View at Publisher · View at Google Scholar · View at PubMed
  53. J. W. Dennis, S. Menawat, J. Von Thron et al., “Efficacy of deep venous thrombosis prophylaxis in trauma patients and identification of high-risk groups,” Journal of Trauma, vol. 35, no. 1, pp. 132–139, 1993. View at Google Scholar
  54. G. R. Upchurch Jr., R. H. Demling, J. Davies, J. D. Gates, and J. B. Knox, “Efficacy of subcutaneous heparin in prevention of venous thromboembolic events in trauma patients,” American Surgeon, vol. 61, no. 9, pp. 749–755, 1995. View at Google Scholar
  55. L. M. Napolitano, V. S. Garlapati, S. O. Heard et al., “Asymptomatic deep venous thrombosis in the trauma patient: Is an aggressive screening protocol justified?” Journal of Trauma, vol. 39, no. 4, pp. 651–659, 1995. View at Publisher · View at Google Scholar
  56. G. C. Velmahos, J. Kern, L. S. Chan et al., “Prevention of venous thromboembolism after injury: an evidence-based report—part I: analysis of risk factors and evaluation of the role of vena caval filters,” Journal of Trauma, vol. 49, no. 1, pp. 132–139, 2000. View at Google Scholar
  57. J. D. Arnold, B. W. Dart, D. E. Barker et al., “Unfractionated heparin three times a day versus enoxaparin in the prevention of deep vein thrombosis in trauma patients,” American Surgeon, vol. 76, no. 6, pp. 563–570, 2010. View at Google Scholar
  58. J. I. Weitz, “Low-molecular-weight heparins,” New England Journal of Medicine, vol. 337, no. 10, pp. 688–698, 1997. View at Publisher · View at Google Scholar · View at PubMed
  59. A. Mayer, M. Hansen, D. Peetz et al., “Prevention of thromboembolism in trauma surgery by dose adjustment of low molecular weight heparin depending on levels of TAT and D-dimer,” Unfallchirurg, vol. 106, no. 12, pp. 1020–1028, 2003. View at Publisher · View at Google Scholar · View at PubMed
  60. M. M. Knudson, F. R. Lewis, A. Clinton, K. Atkinson, and J. Megerman, “Prevention of venous thromboembolism in trauma patients,” Journal of Trauma, vol. 37, no. 3, pp. 480–487, 1994. View at Google Scholar
  61. T. H. Schwarcz, R. C. Quick, D. J. Minion, P. A. Kearney, C. J. Kwolek, and E. D. Endean, “Enoxaparin treatment in high-risk trauma patients limits the utility of surveillance venous duplex scanning,” Journal of Vascular Surgery, vol. 34, no. 3, pp. 447–452, 2001. View at Publisher · View at Google Scholar · View at PubMed
  62. D. Green, M. Y. Lee, A. C. Lim et al., “Prevention of thromboembolism after spinal cord injury using low-molecular-weight heparin,” Annals of Internal Medicine, vol. 113, no. 8, pp. 571–574, 1990. View at Google Scholar
  63. A. B. Hill, B. Garber, G. Dervin, and A. Howard, “Heparin prophylaxis for deep venous thrombosis in a patient with multiple injuries: an evidence-based approach to a clinical problem,” Canadian Journal of Surgery, vol. 45, no. 4, pp. 282–287, 2002. View at Google Scholar
  64. S. A. Sems, B. A. Levy, K. Dajani, D. A. Herrera, and D. C. Templeman, “Incidence of deep venous thrombosis after temporary joint spanning external fixation for complex lower extremity injuries,” The Journal of trauma, vol. 66, no. 4, pp. 1164–1166, 2009. View at Google Scholar
  65. D. Warwick, “Thromboembolic prophylaxis in orthopaedic trauma patients: a comparison between fixed dose and an individually adjusted dose of a low molecular weight heparin,” Injury, vol. 27, no. 6, pp. 385–390, 1996. View at Publisher · View at Google Scholar
  66. D. Malinoski, F. Jafari, T. Ewing et al., “Standard prophylactic enoxaparin dosing leads to inadequate anti-Xa levels and increased deep venous thrombosis rates in critically Ill trauma and surgical patients,” Journal of Trauma, vol. 68, no. 4, pp. 874–879, 2010. View at Publisher · View at Google Scholar · View at PubMed
  67. R. Autar, “A review of venous thromboprophylaxis in patients undergoing hip fracture surgery (HFS),” International Journal of Orthopaedic and Trauma Nursing, vol. 14, no. 2, pp. 88–95, 2010. View at Publisher · View at Google Scholar
  68. A. G. G. Turpie, “The safety of fondaparinux for the prevention and treatment of venous thromboembolism,” Expert Opinion on Drug Safety, vol. 4, no. 4, pp. 707–721, 2005. View at Publisher · View at Google Scholar · View at PubMed
  69. B. I. Eriksson, K. A. Bauer, M. R. Lassen, and A. G. G. Turpie, “Fondaparinux compared with enoxaparin for the prevention of venous thromboembolism after hip-fracture surgery,” New England Journal of Medicine, vol. 345, no. 18, pp. 1298–1304, 2001. View at Publisher · View at Google Scholar · View at PubMed
  70. B. I. Eriksson, M. R. Lassen, and C. W. Colwell Jr., “Efficacy of fondaparinux for thromboprophylaxis in hip fracture patients,” Journal of Arthroplasty, vol. 19, no. 7, pp. 78–81, 2004. View at Publisher · View at Google Scholar
  71. B. Xu, “DVT in acute stroke: the use of graduated compression stockings,” Australian Family Physician, vol. 39, no. 7, pp. 485–487, 2010. View at Google Scholar
  72. R. J. Morris and J. P. Woodcock, “Intermittent pneumatic compression or graduated compression stockings for deep vein thrombosis prophylaxis? A systematic review of direct clinical comparisons,” Annals of Surgery, vol. 251, no. 3, pp. 393–396, 2010. View at Publisher · View at Google Scholar · View at PubMed
  73. A. Rahman, M. C. Colak, L. Üstünel, M. Koc, E. Kocakoc, and C. Colak, “A comparison of different treatment managements in patients with acute deep vein thrombosis by the effects on enhancing venous outflow in the lower limb,” Medical Science Monitor, vol. 15, no. 11, pp. CR588–CR593, 2009. View at Google Scholar
  74. G. Arpaia, M. Carpenedo, R. Pistelli, O. Mastrogiacomo, C. Cimminiello, and G. Agnelli, “Attitudes to prescribing compression stockings for patients with acute dvt: the MASTER registry,” Journal of Thrombosis and Thrombolysis, vol. 28, no. 4, pp. 389–393, 2009. View at Publisher · View at Google Scholar · View at PubMed
  75. L. Walker and S. Lamont, “Graduated compression stockings to prevent deep vein thrombosis,” Nursing Standard, vol. 22, no. 40, pp. 35–38, 2008. View at Google Scholar
  76. R. P. Pitto and S. Young, “Foot pumps without graduated compression stockings for prevention of deep-vein thrombosis in total joint replacement: efficacy, safety and patient compliance—a comparative, prospective clinical trial,” International Orthopaedics, vol. 32, no. 3, pp. 331–336, 2008. View at Publisher · View at Google Scholar · View at PubMed
  77. R. P. Pitto and S. Young, “Foot-pumps without graduated compression stockings for prevention of deep-vein thrombosis in total joint replacement: efficacy, safety and patient compliance—a comparative, prospective clinical trial (International Orthopaedics DOI: 10.1007/s00264-007-0326-9),” International Orthopaedics, vol. 32, no. 3, p. 337, 2008. View at Publisher · View at Google Scholar
  78. A. Sachdeva, M. Dalton, S. V. Amaragiri, and T. Lees, “Elastic compression stockings for prevention of deep vein thrombosis,” Cochrane Database of Systematic Reviews, vol. 7, Article ID CD001484, 2010. View at Google Scholar
  79. G. C. Velmahos, J. Nigro, R. Tatevossian et al., “Inability of an aggressive policy of thromboprophylaxis to prevent deep venous thrombosis (DVT) in critically injured patients: are current methods of DVT prophylaxis insufficient?” Journal of the American College of Surgeons, vol. 187, no. 5, pp. 529–533, 1998. View at Publisher · View at Google Scholar
  80. K. Gersin, G. A. Grindlinger, V. Lee, R. C. Dennis, S. K. Wedel, and R. Cachecho, “The efficacy of sequential compression devices in multiple trauma patients with severe head injury,” Journal of Trauma, vol. 37, no. 2, pp. 205–208, 1994. View at Google Scholar
  81. C. G. Fisher, P. A. Blachut, A. J. Salvian, R. N. Meek, and P. J. O'Brien, “Effectiveness of pneumatic leg compression devices for the prevention of thromboembolic disease in orthopaedic trauma patients: a prospective, randomized study of compression alone versus no prophylaxis,” Journal of orthopaedic trauma, vol. 9, no. 1, pp. 1–7, 1995. View at Google Scholar
  82. M. Kurtoglu, H. Yanar, Y. Bilsel et al., “Venous thromboembolism prophylaxis after head and spinal trauma: Intermittent pneumatic compression devices versus low molecular weight heparin,” World Journal of Surgery, vol. 28, no. 8, pp. 807–811, 2004. View at Publisher · View at Google Scholar · View at PubMed
  83. N. Latronico and M. Berardino, “Thromboembolic prophylaxis in head trauma and multiple-trauma patients,” Minerva Anestesiologica, vol. 74, no. 10, pp. 543–548, 2008. View at Google Scholar
  84. M. M. Knudson, D. Morabito, G. D. Paiement, and S. Shackleford, “Use of low molecular weight heparin in preventing thromboembolism in trauma patients,” Journal of Trauma, vol. 41, no. 3, pp. 446–459, 1996. View at Google Scholar
  85. J. O. Anglen, C. Bagby, and R. George, “A randomized comparison of sequential-gradient calf compression with intermittent plantar compression for prevention of venous thrombosis in orthopedic trauma patients: preliminary results,” American Journal of Orthopedics (Belle Mead, N.J.), vol. 27, no. 1, pp. 53–58, 1998. View at Google Scholar
  86. D. A. Spain, T. M. Bergamini, J. F. Hoffmann, E. H. Carrillo, and J. D. Richardson, “Comparison of sequential compression devices and foot pumps for prophylaxis of deep venous thrombosis in high-risk trauma patients,” American Surgeon, vol. 64, no. 6, pp. 522–526, 1998. View at Google Scholar
  87. J. P. Stannard, R. R. Lopez-Ben, D. A. Volgas et al., “Prophylaxis against deep-vein thrombosis following trauma: a prospective, randomized comparison of mechanical and pharmacologic prophylaxis,” Journal of Bone and Joint Surgery. Series A, vol. 88, no. 2, pp. 261–266, 2006. View at Publisher · View at Google Scholar · View at PubMed
  88. R. J. Winchell, D. B. Hoyt, J. C. Walsh et al., “Risk factors associated with pulmonary embolism despite routine prophylaxis: implications for improved protection,” Journal of Trauma, vol. 37, no. 4, pp. 600–606, 1994. View at Google Scholar
  89. L. J. Greenfield and B. A. Michna, “Twelve-year clinical experience with the Greenfield vena caval filter,” Surgery, vol. 104, no. 4, pp. 706–712, 1988. View at Google Scholar
  90. F. B. Rogers, S. R. Shackford, M. A. Ricci, J. T. Wilson, and S. Parsons, “Routine prophylactic vena cava filter insertion in severely injured trauma patients decreases the incidence of pulmonary embolism,” Journal of the American College of Surgeons, vol. 180, no. 6, pp. 641–647, 1995. View at Google Scholar
  91. J. L. Rodriguez, J. M. Lopez, M. C. Proctor et al., “Early placement of prophylactic vena caval filters in injured patients at high risk for pulmonary embolism,” Journal of Trauma, vol. 40, no. 5, pp. 797–802, 1996. View at Google Scholar
  92. L. P. Sue, J. W. Davis, and S. N. Parks, “Iliofemoral venous injuries: an indication for prophylactic caval filter placement,” Journal of Trauma, vol. 39, no. 4, pp. 693–695, 1995. View at Publisher · View at Google Scholar
  93. S. R. Shackford, A. Cook, F. B. Rogers, B. Littenberg, and T. Osler, “The increasing use of vena cava filters in adult trauma victims: data from the American College of Surgeons National Trauma Data Bank,” Journal of Trauma, vol. 63, no. 4, pp. 764–769, 2007. View at Publisher · View at Google Scholar · View at PubMed
  94. S. Khansarinia, “Prophylactic greenfield filter placement in selected high-risk trauma patients,” Journal of Vascular Surgery, vol. 22, no. 3, pp. 231–236, 1995. View at Publisher · View at Google Scholar
  95. T. S. Helling, S. Kaswan, S. L. Miller, and J. F. Tretter, “Practice patterns in the use of retrievable inferior vena cava filters in a trauma population: a single-center experience,” Journal of Trauma, vol. 67, no. 6, pp. 1293–1296, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  96. S. McKenzie, H. Gibbs, D. Leggett et al., “An Australian experience of retrievable inferior vena cava filters in patients with increased risk of thromboembolic disease,” International Angiology, vol. 29, no. 1, pp. 53–57, 2010. View at Google Scholar · View at Scopus
  97. P. H. Gorman, S. F. Qadri, and A. Rao-Patel, “Prophylactic inferior vena cava (IVC) filter placement may increase the relative risk of deep venous thrombosis after acute spinal cord injury,” The Journal of Trauma, vol. 66, no. 3, pp. 707–712, 2009. View at Google Scholar · View at Scopus
  98. H. A. Phelan, R. P. Gonzalez, W. C. Scott, C. Q. White, M. McClure, and J. P. Minei, “Long-term follow-up of trauma patients with permanent prophylactic vena cava filters,” The Journal of Trauma, vol. 67, no. 3, pp. 485–489, 2009. View at Google Scholar · View at Scopus
  99. D. Rosenthal, P. V. Kochupura, E. D. Wellons, A. B. Burkett, and W. C. Methodius-Rayford, “Günther tulip and celect IVC filters in multiple-trauma patients,” Journal of Endovascular Therapy, vol. 16, no. 4, pp. 494–499, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  100. R. A. Cherry, P. A. Nichols, T. M. Snavely, M. T. David, and F. C. Lynch, “Prophylactic inferior vena cava filters: do they make a difference in trauma patients?” The Journal of Trauma, vol. 65, no. 3, pp. 544–548, 2008. View at Google Scholar · View at Scopus
  101. J. Hirsh, G. Guyatt, and S. Z. Lewis, “Reflecting on eight editions of the American College of Chest Physicians antithrombotic guidelines,” Chest, vol. 133, no. 6, pp. 1293–1295, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  102. W. H. Geerts, D. Bergqvist, G. F. Pineo et al., “Prevention of venous thromboembolism: American College of Chest Physicians evidence-based clinical practice guidelines (8th edition),” Chest, vol. 133, no. 6, pp. 381S–453S, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  103. J. G. Cushman, N. Agarwal, T. C. Fabian et al., “Practice management guidelines for the management of mild traumatic brain injury: the EAST practice management guidelines work group,” Journal of Trauma, vol. 51, no. 5, pp. 1016–1026, 2001. View at Google Scholar · View at Scopus