Review Article

Evaluating the Role of Compression Stockings in Preventing Post thrombotic Syndrome: A Review of the Literature

Table 2

Clinical Scales for assessing the presence and severity of PTS.

PTS ScaleCriteria used to diagnose PTSComments

Ginsberg et al. [34]Pain and swelling of limb > 1 month duration, typical character (worse at end of day or with prolonged sitting/standing, better after night’s rest and leg elevation) that occurs ≥ 6 months after acute DVT
AND
Objective evidence of valvular incompetence (diagnosed via plethysmography or venous Doppler):
 (i) if both criteria are present, PTS is diagnosed,
 (ii) Global Rating Questionnaire used to rate overall improvement or
 worsening of PTS over time
Developed specifically for PTS; does not rate the severity of PTS

Villalta et al. [35]5 Symptoms (pain, cramps, heaviness, pruritus, paresthesia)
6 signs (edema, skin induration, hyperpigmentation, ectasia, redness, pain during calf compression)
Each rated as 0 (absent), 1 (mild), 2 (moderate) or 3 (Severe)
Points are summed. A total score of
0–4: No PTS
5–14: Mild/Moderate PTS
≥15, or presence of ulcer: Severe PTS
Developed specifically for PTS; rates the severity of PTS

CEAP Classification* [36, 37]Patients with chronic venous disease classified into 1 of 7 clinical classes (Class 0–6) according to the presence of clinical signs. Each class may include signs present in lower-order class.
Class:
 (0) Symptoms only; no visible or palpable signs of venous disease
 (1) Telangiectasias, reticular veins, malleolar flare
 (2) Varicose veins
 (3) Edema, no skin changes
 (4) Skin changes (e.g., pigmentation, eczema, lipodermatosclerosis)
 (5) Skin changes with healed ulcer
 (6) Skin changes with active ulcer
Each clinical class is then subclassified as to:
Etiology (congenital, primary, secondary)
Anatomy (superficial, deep, perforator veins)
Pathophysiology (reflux, obstruction, both)
Was developed for chronic venous disease in general and not for PTS; does not rate the severity of PTS

PTS = postthrombotic syndrome; *CEAP: Clinical-Etiology-Anatomic-Pathophysiologic. Modifications of CEAP (clinical severity score, venous segmental disease score) have been proposed.
Increasing CEAP class is intended to reflect increased severity of signs of chronic venous disease; symptoms and their severity are not considered.