The Role of Dermcidin Isoform 2: A Two-Faceted Atherosclerotic Risk Factor for Coronary Artery Disease and the Effect of Acetyl Salicylic Acid on It

Figure 2

The effect of injection of dermcidin to the rabbits on the systolic and diastolic pressures and on the plasma NO level at different times after the injection of the protein. The electrophoretically purified dermcidin was injected to the circulation of “normal” rabbits (1.0 nmol/kg body weight). Both systolic and diastolic pressures and the plasma NO levels were determined at different time after the administration of the oxidative stress protein. The results shown are mean ± SD of six different experiments 3 times each using 6 different rabbits.