Review Article

The Role of Thrombophilia in Pregnancy

Table 2

Incidence of pregnancy-associated VTE with inherited thrombophilia.

ThrombophiliaPregnancy (%/pregnancy)Overall (%/year)

Factor V Leiden heterozygous2.1 (0.7–4.9)0.5 (0.1–1.3)
Prothrombin gene mutation heterozygous2.3 (0.8–5.3)0.4 (0.1–1.1)
ATIII, protein C, or protein S deficiency4.1 (1.7–8.3)1.5 (0.7–2.8)