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Tuberculosis Research and Treatment
Volume 2010, Article ID 241659, 5 pages
http://dx.doi.org/10.1155/2010/241659
Research Article

Yield of Smear Microscopy and Radiological Findings of Male and Female Patients with Tuberculosis in Abuja, Nigeria

1Zankli Medical Centre, Plot 1021, B5 Shehu Yar'adua Way, P.O. Box 7745, Abuja, Nigeria
2Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK
3Faculty of Medicine, University of Liverpool, Liverpool L693Bx, UK

Received 22 December 2009; Revised 20 May 2010; Accepted 18 June 2010

Academic Editor: William N. Rom

Copyright © 2010 Lovett Lawson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. To describe the yield of smear-microscopy and radiological findings by male and female patients with symptoms of tuberculosis in Abuja, Nigeria. Methods. Patients ≥15 years old with cough for >3 weeks submitted 3 sputum samples for smear microscopy. One specimen was cultured using MGIT-960. All patients had lung X-rays and screened for HIV. Results. were more likely to be smear-positive than females (262/774 [34%] and 137/547 [25%], 𝑃 < . 0 1 ), but similar proportions of males and females were culture-positive (437/691 [63%] and 294/495 [59%], 𝑃 = . 0 9 ). 317/626 (50.6%) males and 249/419 (59.4%) females were HIV-positive ( 𝑃 < . 0 0 5 ). Among culture-positives patients, HIV-infected males were less likely to have positive smears than HIV-negative males (49.2% versus 66%, 𝑃 = . 0 0 1 ). Among females, smear positivity did not vary with HIV (46.4% for HIV-positive and 52.9% for HIV-negative, 𝑃 = . 3 8 ). Of 274 culture-confirmed TB cases, 226 (82.5%) had cavities, and 271 (99%) had ≥1 lung areas affected. HIV-positive males were more likely to have lung cavities than HIV-positive females (85% versus 69%, 𝑃 < . 0 4 ) and to have ≥3 lung areas affected ( 𝑃 = . 0 3 ). Conclusion. Differences in the yield of smear-microscopy, culture and X-rays on presentation are due to several factors including HIV coinfection and gender.