Research Article

Mycobacterium tuberculosis Complex Genotype Diversity and Drug Resistance Profiles in a Pediatric Population in Mexico

Table 3

Description of M. tuberculosis complex shared types in pediatric patients ( đť‘› = 9 0 ).

SITSpoligotype descriptionOctal numberTotal (%) in this study% in this study versus databaseCladeClustered versus unique patterns

1239042.tab.003a0000000000037711 (1.1)0.02BeijingUnique
3239042.tab.003b0000000077207711 (1.1)1.09H3Unique
17239042.tab.003c6777376077607711 (1.1)0.17LAM2Unique
20239042.tab.003d6777776077607711 (1.1)0.14LAM1Unique
33239042.tab.003e7761776077607712 (2.2)0.19LAM3Clustered
34239042.tab.003f7763777777607711 (1.1)0.13SUnique
42239042.tab.003g77777760776077112 (13.3)0.44LAM9Clustered
47239042.tab.003h7777777740207714 (4.0)0.32H1Clustered
49239042.tab.003i7777777777207312 (2.2)1.46H3Clustered
50239042.tab.003j7777777777207713 (3.3)0.11H3Clustered
53239042.tab.003k7777777777607719 (10.0)0.18T1Clustered
70239042.tab.003l7000767777606713 (3.3)2.59X3Clustered
81239042.tab.003m7773776077607711 (1.1)3.23LAM9Unique
91239042.tab.003n7000367777607711 (1.1)0.42X3Unique
92239042.tab.003o7000767777607711 (1.1)0.25X3Unique
95239042.tab.003p7777776075607311 (1.1)2.56LAM6Unique
119239042.tab.003q7777767777607714 (4.4)0.39X1Clustered
130239042.tab.003r7761776077607311 (1.1)1.1LAM3Unique
239239042.tab.003s7777777777600311 (1.1)1.92T1Unique
373239042.tab.003t7777777677607711 (1.1)1.75T1Unique
398239042.tab.003u7777776077606311 (1.1)8.33LAM4Unique
450239042.tab.003v7777767700000001 (1.1)1.19Unique
804239042.tab.003w4777777777607711 (1.1)5T1Unique
1166239042.tab.003x7773777777607711 (1.1)2.63T1Unique
1193239042.tab.003y7777776777737712 (2.2)50Manu1Clustered
1243239042.tab.003z7773777777207712 (2.2)14.29H3Clustered
1277239042.tab.003aa7777772077607711 (1.1)4.55LAM9Unique
1626239042.tab.003ab7777777767607711 (1.1)12.5T1Unique
1711239042.tab.003ac6773376077607711 (1.1)25LAM2Unique
2188239042.tab.003ad7773777777607311 (1.1)25T2Unique
2337239042.tab.003ae7773777740207711 (1.1)16.67H1Unique
2496239042.tab.003af7773677777607711 (1.1)7.14T1Unique
3079*239042.tab.003ag4763636367562002 (2.2)100BOVISClustered
3080*239042.tab.003ah7773777777637712 (2.2)66.67Manu2Clustered
3089*239042.tab.003ai3377777777607711 (1.1)50T1Unique
3090*239042.tab.003aj6777737777776001 (1.1)50BOVISUnique

Shared types (SIT) followed by an asterisk indicate “newly created” shared types ( 𝑛 = 4 ) due to 2 or more strains belonging to an identical new pattern within this study (SIT3079, SIT3080), or a unique strain from this study matching with another orphan in the database (SIT3089 matched an orphan from Peru; SIT3090 matched an orphan from USA). Note that SIT3080 was created by 2 strains belonging to an identical pattern within this study that also matched an orphan from Saudi Arabia.
Clade designations are according to SITVIT2 database. Unk: unknown patterns within major clades described in SITVIT2.
Clustered versus unique patterns; clustered strains correspond to a similar spoligotype pattern shared by 2 or more strains “within this study”; as opposed to unique strains harboring a spoligotype pattern that does not match with another strain from this study. Unique strains matching a preexisting pattern in the SITVIT2 database are classified as SITs, whereas in case of no match, they are designated as “orphan” (see Table 1).