Rapid Diagnosis of Pulmonary and Extrapulmonary Tuberculosis in HIV-Infected Patients. Comparison of LED Fluorescent Microscopy and the GeneXpert MTB/RIF Assay in a District Hospital in India

Table 1

Positive results utilizing light-emitting diode fluorescent microscopy and Xpert MTB/RIF assay.

	Total	Smear positive		Xpert positive		Absolute difference	Ratio Xpert/LED
	𝑁	𝑁	% (95% CI)	𝑁	% (95% CI)	% (95% CI)	(95% CI)
Sputum	166	106	63.9 (56.2 to 70.8)	124	74.7 (67.5 to 80.8)	10.8 (5.2 to 16.5)	1.17 (1.08 to 1.26)
Sputum x3	166	116	69.9 (62.4–76.4)	124	74.7 (67.5 to 80.8)	4.8 (0.6 to 9.1)	1.07 (1.02 to 1.13)
Extrapulmonary	253	23	9.1 (6.1 to 13.3)	74	29.2 (24 to 35.2)	20.2 (14.8 to 25.5)	3.22 (2.29 to 4.52)
CSF	142	3	2.1 (0.7 to 6.4)	35	24.6 (18.2 to 32.4)	22.5 (15 to 30.1)	11.67 (3.95 to 34.42)
Pleural fluid	75	10	13.3 (7.3 to 23.1)	24	32 (22.4 to 43.4)	18.7 (8.5 to 28.8)	2.4 (1.49 to 3.85)
Ascitic fluid	18	2	11.1 (2.8 to 35.4)	5	27.8 (12 to 52)	16.7 (−6.1 to 39.4)	2.5 (0.85 to 7.31)
Pus	10	7	70 (37.5 to 90.1)	8	80 (45.8 to 95)	10 (−18.6 to 38.6)	1.14 (0.88 to 1.49)
Stool	8	1	12.5 (1.7 to 53.9)	2	25 (6.3 to 62.4)	12.5 (−22.9 to 47.9)	2 (0.5 to 8)
Total	419	129	30.8 (26.5 to 35.4)	198	47.3 (42.5 to 52.1)	16.5 (12.6 to 20.3)	1.53 (1.38 to 1.7)

CI: confidence interval; LED: light-emitting diode fluorescent microscopy; CSF: cerebrospinal fluid.