Research Article
Profile, Outcomes, and Determinants of Unsuccessful Tuberculosis Treatment Outcomes among HIV-Infected Tuberculosis Patients in a Nigerian State
Table 2
Predictors of unsuccessful tuberculosis treatment outcomes among 233 rural TB/HIV patients in Ebonyi State, Nigeria, 2011-2012.
| | Characteristics | Successful outcome
(%) | Unsuccessful outcome
(%) | Crude OR
(95% CI) | Adjusted OR
(95% CI) | Adjusted value |
| | Age (years) | | | | | | | ≤40 | 106 (60.6) | 69 (39.4) | 1.07 (0.6–2.0) | 1.06 (0.5–2.1) | 0.86 | | >40 | 36 (62.1) | 22 (37.9) | 1 | 1 | | | Gender | | | | | | | Female | 65 (58.0) | 47 (42.0) | 1.26 (0.8–2.1) | 1.26 (0.7–2.3) | 0.43 | | Male | 77 (63.6) | 44 (36.8) | 1 | 1 | | | Facility | | | | | | | Public | 23 (38.3) | 37 (61.7) | 3.6 (1.9–6.5) | 3.8 (1.9–7.7) | <0.001 | | Private | 119 (68.8) | 54 (31.2) | 1 | 1 | | | Treatment category | | | | | | | New | 132 (60.8) | 85 (39.2) | 1.07 (0.4–3.1) | 1.06 (0.4–3.2) | 0.92 | | Previously treated | 10 (62.5) | 6 (37.5) | 1 | 1 | | | Type of TB | | | | | | | Pulmonary | 139 (61.8) | 86 (38.2) | 1 | 1 | | | Extrapulmonary | 3 (37.5) | 5 (62.5) | 2.7 (0.6–11.6) | 1.2 (0.3–6.0) | 0.80 | | Anti-TB regimen | | | | | | | Regimen 1 | 72 (55.8) | 57 (44.2) | 1.6 (0.9–2.8) | 1.7 (0.9–3.2) | 0.096 | | Regimen 2 | 70 (67.3) | 34 (32.7) | 1 | 1 | | | Received ART | | | | | | | Yes | 47 (58.8) | 33 (41.2) | 1.2 (0.7–2.0) | 1.2 (0.5–2.5) | 0.71 | | No | 95 (62.1) | 58 (37.9) | 1 | 1 | | | Received CPT | | | | | | | Yes | 79 (60.3) | 52 (39.7) | 1.06 (0.6–1.8) | 1.0 (0.5–2.0) | 0.98 | | No | 63 (61.8) | 39 (38.2) | 1 | 1 | |
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Regimen 1: 2RHZE/6EH; regimen 2: 2RHZE/4RH (R: rifampicin, H: isoniazid, Z: pyrazinamide, and E: ethambutol); OR: odds ratio; ART: antiretroviral therapy; TB: tuberculosis; HIV: human immunodeficiency virus; CPT: cotrimoxazole preventive therapy.
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