Table of Contents Author Guidelines Submit a Manuscript
Table of Contents Alerts

To receive news and publication updates for Tuberculosis Research and Treatment, enter your email address in the box below.

Tuberculosis Research and Treatment
Volume 2014, Article ID 858396, 6 pages
http://dx.doi.org/10.1155/2014/858396
Research Article

Histopathological Findings in Immunohistological Staining of the Granulomatous Tissue Reaction Associated with Tuberculosis

Shirin Karimi,1 Masoud Shamaei,2 Mihan Pourabdollah,3 Makan Sadr,4 Mehrdad Karbasi,3 Arda Kiani,4 and Moslem Bahadori5

1Mycobacteriology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
2Clinical Tuberculosis and Epidemiology Research Center, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
4Tracheal Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
5Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran

Received 7 September 2013; Revised 23 October 2013; Accepted 30 October 2013; Published 5 January 2014

Academic Editor: Juraj Ivanyi

Copyright © 2014 Shirin Karimi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. T. Programme, Global Tuberculosis Control: WHO Report: Global Tuberculosis Programme, World Health Organization, 2010.
  2. E. L. Corbett, C. J. Watt, N. Walker et al., “The growing burden of tuberculosis: global trends and interactions with the HIV epidemic,” Archives of Internal Medicine, vol. 163, no. 9, pp. 1009–1021, 2003. View at Publisher · View at Google Scholar · View at Scopus
  3. A. Trusov, R. Bumgarner, R. Valijev et al., “Comparison of Lumin™ LED fluorescent attachment, fluorescent microscopy and Ziehl-Neelsen for AFB diagnosis,” International Journal of Tuberculosis and Lung Disease, vol. 13, no. 7, pp. 836–841, 2009. View at Google Scholar · View at Scopus
  4. A. M. Attallah, C. A. A. Malak, H. Ismail, A. H. El-Saggan, M. M. Omran, and A. A. Tabll, “Rapid and simple detection of a Mycobacterium tuberculosis circulating antigen in serum using dot-ELISA for field diagnosis of pulmonary tuberculosis,” Journal of Immunoassay and Immunochemistry, vol. 24, no. 1, pp. 73–87, 2003. View at Publisher · View at Google Scholar · View at Scopus
  5. J. M. Dora, G. Geib, R. Chakr et al., “Polymerase chain reaction as a useful and simple tool for rapid diagnosis of tuberculous meningitis in a Brazilian tertiary care hospital,” Brazilian Journal of Infectious Diseases, vol. 12, no. 3, pp. 245–247, 2008. View at Google Scholar · View at Scopus
  6. A. Mishra, A. Singhal, D. S. Chauhan et al., “Direct detection and identification of Mycobacterium tuberculosis and Mycobacterium bovis in bovine samples by a novel nested PCR assay: correlation with conventional techniques,” Journal of Clinical Microbiology, vol. 43, no. 11, pp. 5670–5678, 2005. View at Publisher · View at Google Scholar · View at Scopus
  7. J. S. Pedersen, I. Clarke, and J. Mills, “Improved detection of mycobacteria species in formalin-fixed tissue sections,” Histopathology, vol. 59, no. 5, pp. 993–1005, 2011. View at Publisher · View at Google Scholar · View at Scopus
  8. T. Mustafa, H. G. Wiker, S. G. M. Mfinanga, O. Mørkve, and L. Sviland, “Immunohistochemistry using a Mycobacterium tuberculosis complex specific antibody for improved diagnosis of tuberculous lymphadenitis,” Modern Pathology, vol. 19, no. 12, pp. 1606–1614, 2006. View at Publisher · View at Google Scholar · View at Scopus
  9. H. D'Avila, C. M. Maya-Monteiro, and P. T. Bozza, “Lipid bodies in innate immune response to bacterial and parasite infections,” International Immunopharmacology, vol. 8, no. 10, pp. 1308–1315, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. S. Logani, D. R. Lucas, J. D. Cheng, H. L. Ioachim, and N. V. Adsay, “Spindle cell tumors associated with mycobacteria in lymph nodes of HIV-positive patients: ‘Kaposi sarcoma with mycobacteria’ and ‘mycobacterial pseudotumor’,” American Journal of Surgical Pathology, vol. 23, no. 6, pp. 656–661, 1999. View at Publisher · View at Google Scholar · View at Scopus
  11. T. Ulrichs, M. Lefmann, M. Reich et al., “Modified immunohistological staining allows detection of Ziehl-Neelsen-negative Mycobacterium tuberculosis organisms and their precise localization in human tissue,” Journal of Pathology, vol. 205, no. 5, pp. 633–640, 2005. View at Publisher · View at Google Scholar · View at Scopus
  12. Á. Somoskövi, J. E. Hotaling, M. Fitzgerald, D. O'Donnell, L. M. Parsons, and M. Salfinger, “Lessons from a proficiency testing event for acid-fast microscopy,” Chest, vol. 120, no. 1, pp. 250–257, 2001. View at Publisher · View at Google Scholar · View at Scopus
  13. R. W. Smithwìck, Laboratory Manual For Acid-Fast Microscopy: Public Health Service, Center For Disease Control, Bureau of Laboratories, 1976.
  14. M. M. Goel and P. Budhwar, “Immunohistochemical localization of mycobacterium tuberculosis complex antigen with antibody to 38 kDa antigen versus Ziehl Neelsen staining in tissue granulomas of extrapulmonary tuberculosis,” The Indian journal of tuberculosis, vol. 54, no. 1, pp. 24–29, 2007. View at Google Scholar · View at Scopus
  15. M. R. Purohit, T. Mustafa, H. G. Wiker, O. Mørkve, and L. Sviland, “Immunohistochemical diagnosis of abdominal and lymph node tuberculosis by detecting Mycobacterium tuberculosis complex specific antigen MPT64,” Diagnostic Pathology, vol. 2, no. 1, article 36, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. A. A. Velayati, P. Farnia, M. R. Masjedi, and G. Konstantinovich, “Morphological modification by tubercle bacilli: no time for denial,” Journal of Infection in Developing Countries, vol. 6, no. 1, pp. 97–99, 2012. View at Google Scholar
  17. K. M. Dobos, E. A. Spotts, F. D. Quinn, and C. H. King, “Necrosis of lung epithelial cells during infection with Mycobacterium tuberculosis is preceded by cell permeation,” Infection and Immunity, vol. 68, no. 11, pp. 6300–6310, 2000. View at Publisher · View at Google Scholar · View at Scopus
  18. S. A. Oracki, J. A. Walker, M. L. Hibbs, L. M. Corcoran, and D. M. Tarlinton, “Plasma cell development and survival,” Immunological Reviews, vol. 237, no. 1, pp. 140–159, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. G. González-Avila, C. Sandoval, M. T. Herrera et al., “Mycobacterium tuberculosis effects on fibroblast collagen metabolism,” Respiration, vol. 77, no. 2, pp. 195–202, 2009. View at Publisher · View at Google Scholar · View at Scopus