Multiplex Analysis of Pro- or Anti-Inflammatory Serum Cytokines and Chemokines in relation to Gender and Age among Tanzanian Tuberculous Lymphadenitis Patients
Table 2
Serum cytokine levels in the adult and paediatric patients with tuberculous lymphadenitis and healthy controls.
Cytokine (pg/mL)
Adult patients () Median (range)
Healthy controls () Median (range)
value
Pediatric patients () Median (range)
value
IFN-
0.0 (0–42.8)
0.0 (0–1.5)
0.001
0.0 (0–40.4)
0.268
TNF-
8.4 (0–352.5)
2.5 (0–51.7)
0.005
3.2 (0–33.4)
0.015
GM-CSF
35.2 (0–506.9)
0.0 (0–379.2)
0.007
0.0 (0–147.9)
0.023
IL-1
48.7 (0–6305.4)
0.0 (0–933.2)
0.004
4.0 (0–610.5)
0.338
IL-2
0.0 (0–28.2)
0.3 (0–16.3)
0.038
1.0 (0–105.6)
0.003
IL-4
0.0 (0–18.5)
0.0 (0–4.3)
0.002
0.0 (0–5.4)
0.208
IL-5
1.0 (0–10.0)
0.5 (0–12.5)
0.559
0.0 (0–1.5)
0.001
IL-6
47.4 (0–25781.5)
0.0 (0–9355.1)
0.000
44.1 (0–587.4)
0.244
IL-8
370.4 (0–386578.0)
65.9 (1.6–2888.2)
0.071
68.2 (0–3551.4)
0.195
IL-10
0.0 (0–29.3)
0.0 (0–36.2)
0.560
0.0 (0–9.9)
0.233
IL-12
0.0 (0–37.8)
2.7 (0–15.3)
0.000
0.0 (0–9.5)
0.701
IL-15
0.0 (0–61.4)
0.0 (0–12.7)
0.812
0.6 (0–53.3)
0.385
IL-17
0.0 (0–133.7)
0
0.282
0
0.262
value for difference between adult patients and healthy controls and value for difference between adult and pediatric patients.
