Tuberculosis Research and Treatment / 2018 / Article / Tab 2

Review Article

Is Chemoprophylaxis for Child Contacts of Drug-Resistant TB Patients Beneficial? A Systematic Review

Table 2

Quality of evidence and results from included studies.

Quality assessment Number of patientsEffect Quality Importance
Number of studiesStudy designRisk of biasInconsistencyIndirectnessImprecisionOther considerationsPreventive therapyNo preventive therapyRelative (95% CI)Absolute (95% CI)

Incidence of TB
2Observational studiesNot seriousNot seriousNot seriousNot seriousStrong association4/182 (2.2%)17/109 (15.6%)RR 0.21 (0.07 to 0.63)123 fewer per 1,000 (from 58 fewer to 145 fewer)⨁⨁⨁◯ Moderate

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