Influence of Seasonality and Circulating Cytokines on Serial QuantiFERON Discordances

Table 1

Correlations between significant cytokines and chemokines with antigen induced IFN-γ level in QFT.

Covariants	Coefficients	value	value	95% confidence interval
Interleukin-7 (IL-7)	−2.305	−1.99	0.047	[−4.58, −0.031]
Interferon-gamma (IFN-γ)	−0.534	−2.2	0.028	[−1.01, −0.059]
Interleukin-2 (IL-2)	−0.026	−0.03	0.972	[−1.527, 1.474]
Granulocyte colony-stimulating factor	−0.007	−2.1	0.036	[−0.014, −0.0004]
Soluble IL-2 receptor alpha (sIL-2Rα)	−0.005	−0.05	0.963	[−0.206, 0.197]
Macrophage inflammatory protein 1β (MIP-1β)	−0.003	−0.32	0.746	[−0.02, 0.014]
Interleukin-6 (IL-6)	0.00004	0.21	0.835	[−0.003, 0.004]
Interleukin-1β (IL-1β)	0.044	2.35	0.019
Interleukin-15 (IL-15)	0.786	0.38	0.706	[−3.302, 4.874]
Interleukin-17 (IL-17)	1.183	1.36	0.173	[−0.519, 2.884]
Interleukin-12p70 (IL-12p70)	4.171	2.2	0.027	[0.463, 7.879]
Interleukin-3 (IL-3)	4.342	3.47	0.001	[1.889, 6.696]
Interleukin-5 (IL-5)	13.133	1.42	0.157	[−5.04, 31.306]
Spring season (March–May)	33.097	4.51	<0.001	[18.725, 47.47]