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Tuberculosis Research and Treatment
Volume 2019, Article ID 3569018, 10 pages
https://doi.org/10.1155/2019/3569018
Research Article

Predictors of Treatment Outcomes among Multidrug Resistant Tuberculosis Patients in Tanzania

1Kilimanjaro Christian Medical University College, P.O. Box 2240, Moshi, Tanzania
2Kibong’oto Infectious Diseases Hospital, P.O. Box 12, Sanya Juu, Tanzania
3Western Zone Blood Transfusion Center, P.O. Box 1782, Tabora, Tanzania

Correspondence should be addressed to Tamary Henry Leveri; moc.oohay@yrnehyramat

Received 1 October 2018; Revised 18 December 2018; Accepted 20 December 2018; Published 12 February 2019

Academic Editor: Isamu Sugawara

Copyright © 2019 Tamary Henry Leveri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. WHO, GLOBAL TUBERCULOSIS REPORT 2016, 2016.
  2. WHO, “The Global Plan to Stop TB: 2011-2015,” 2010, http://www.stoptb.org.
  3. WHO, “Multidrug-Resistant Tuberculosis (MDR-TB) Indicators,” 2010, https://apps.who.int/iris/bitstream/handle/10665/70484/WHO_HTM_TB_2010.11_eng.pdf;jsessionid=5E41E5961BFB7D932AA29BAE85D057DC?sequence=1. View at Publisher · View at Google Scholar
  4. O. S. Elmi, H. Hasan, S. Abdullah, M. Z. Mat Jeab, Z. BA, and N. N. Naing, “Treatment outcomes of patients with multidrug-resistant tuberculosis (MDR- TB) compared with Non-MDR-TB infections in peninsular malaysia,” Malaysian Journal of Medical Sciences, vol. 23, no. 4, pp. 17–25, 2016. View at Publisher · View at Google Scholar
  5. WHO, “WHO treatment guidelines for drug-resistant tuberculosis,” 2016.
  6. P. Isaakidis, E. C. Casas, M. Das, X. Tseretopoulou, E. E. Ntzani, and N. Ford, “Treatment outcomes for HIV and MDR-TB co-infected adults and children: systematic review and meta-analysis,” The International Journal of Tuberculosis and Lung Disease, vol. 19, no. 8, pp. 969–978, 2015. View at Publisher · View at Google Scholar · View at Scopus
  7. Y. Kwon, Y. Kim, G. Suh et al., “Treatment outcomes for HIV‐uninfected patients with multidrug‐resistant and extensively drug‐resistant tuberculosis,” Clinical Infectious Diseases, vol. 47, no. 4, pp. 496–502, 2008. View at Publisher · View at Google Scholar
  8. N. Kwak, H. Kim, C. Yoo, Y. W. Kim, S. K. Han, and J. Yim, “Changes in treatment outcomes of multidrug-resistant tuberculosis,” The International Journal of Tuberculosis and Lung Disease, vol. 19, no. 5, pp. 525–530, 2015. View at Publisher · View at Google Scholar
  9. K. T. Kibret, Y. Moges, P. Memiah, and S. Biadgilign, “Treatment outcomes for multidrug-resistant tuberculosis under DOTS-Plus: a systematic review and meta-analysis of published studies,” Infectious Diseases of Poverty, vol. 6, no. 1, p. 7, 2017. View at Publisher · View at Google Scholar
  10. T. E. Tupasi, A. M. Garfin, E. V. Kurbatova et al., “Factors associated with loss to follow-up during treatment for multidrug-resistant tuberculosis, the philippines, 2012–2014,” Emerging Infectious Diseases, vol. 22, no. 3, pp. 491–502, 2016. View at Publisher · View at Google Scholar
  11. S. Tang, S. Tan, L. Yao et al., “Risk factors for poor treatment outcomes in patients with MDR-TB and XDR-TB in China: retrospective multi-center investigation,” PLoS ONE, vol. 8, no. 12, Article ID e82943, pp. 1–8, 2013. View at Publisher · View at Google Scholar
  12. K. Schnippel, K. Shearer, D. Evans, R. Berhanu, S. Dlamini, and N. Ndjeka, “Predictors of mortality and treatment success during treatment for rifampicin-resistant tuberculosis within the South African National TB Programme, 2009 to 2011: a cohort analysis of the national case register,” International Journal of Infectious Diseases, vol. 39, pp. 89–94, 2015. View at Publisher · View at Google Scholar
  13. M. A. Khan, S. Mehreen, A. Basit et al., “Predictors of poor outcomes among patients treated for multidrug- resistant tuberculosis at tertiary care hospital in Pakistan,” American-Eurasian Journal of Toxicological Sciences, vol. 7, no. 3, pp. 162–172, 2015. View at Google Scholar
  14. B. Sawadogo, K. S. Tint, M. Tshimanga, L. Kuonza, and L. Ouedraogo, “Risk factors for tuberculosis treatment failure among pulmonary tuberculosis patients in four health regions of Burkina Faso, 2009: case control study,” Pan African Medical Journal, vol. 21, pp. 1–14, 2015. View at Publisher · View at Google Scholar
  15. K. Kliiman and A. Altraja, “Predictors of poor treatment outcome in multi- and extensively drug-resistant pulmonary TB,” European Respiratory Journal, vol. 33, no. 5, pp. 1085–1094, 2009. View at Publisher · View at Google Scholar
  16. G. Kuchukhidze, A. M. V. Kumar, P. de Colombani et al., “Risk factors associated with loss to follow-up among multidrug- resistant tuberculosis patients in Georgia,” Public Health Action, vol. I(4), pp. 249–251, 2014. View at Google Scholar
  17. A. Periasamy and K. A. P. Viswanatham, “Pulmonary & respiratory medicine predictors of outcome in drug resistant tuberculosis patients,” Journal of Pulmonary and Respiratory Medicine, vol. 7, no. 7, pp. 1–4, 2017. View at Publisher · View at Google Scholar
  18. A. Javaid, Z. Shaheen, M. Shafqat, A. H. Khan, and N. Ahmad, “Risk factors for high death and loss-to-follow-up rates among patients with multidrug-resistant tuberculosis at a programmatic management unit,” American Journal of Infection Control, vol. 45, no. 2, pp. 190–193, 2017. View at Publisher · View at Google Scholar
  19. E. Elliott, H. R. Draper, P. Baitsiwe, and M. M. Claassens, “Factors affecting treatment outcomes in drug-resistant tuberculosis cases in the Northern Cape, South Africa,” Public Health Action, vol. 4, no. 3, pp. 201–203, 2014. View at Publisher · View at Google Scholar
  20. K. S. Shringarpure, P. Isaakidis, K. D. Sagili, R. K. Baxi, and N. Mistry, “Loss-to-follow-up on multidrug resistant tuberculosis treatment in Gujarat, India: the when and who of it,” PLoS ONE, vol. 10, no. 7, Article ID e0132543, pp. 1–10, 2015. View at Publisher · View at Google Scholar
  21. J. C. Brust, A. R. Berman, B. Zalta et al., “Chest radiograph findings and time to culture conversion in patients with multidrug-resistant tuberculosis and hiv in tugela ferry, south africa,” PLoS ONE, vol. 8, no. 9, Article ID e73975, pp. 1–8, 2013. View at Publisher · View at Google Scholar
  22. R. R. Kempker, A. S. Rabin, K. Nikolaishvili et al., “Additional drug resistance in Mycobacterium tuberculosis isolates from resected cavities among patients with multidrug-resistant or extensively drug-resistant pulmonary tuberculosis,” Clinical Infectious Diseases, vol. 54, no. 6, pp. e51–e54, 2012. View at Publisher · View at Google Scholar · View at Scopus
  23. A. Icksan, M. Sonang Napitupulu, M. Nawas, and F. Nurwidya, “Chest X-ray findings comparison between multi-drug-resistant tuberculosis and drug-sensitive tuberculosis,” Journal of Natural Science, Biology and Medicine, vol. 9, no. 1, pp. 42–46, 2018. View at Publisher · View at Google Scholar
  24. Y. Balabanova, R. Coker, I. Fedorin et al., “Variability in interpretation of chest radiographs among Russian study,” Peer-Reviewed Medical Journal, vol. 331, pp. 1–4, 2005. View at Google Scholar
  25. V. K. Dhingra, S. Rajpal, A. Mittal, and M. Hanif, “Outcome of multi-drug resistant tuberculosis cases treated by individualized regimens at a tertiary level clinic,” The Indian Journal of Tuberculosis, vol. 55, no. 1, pp. 15–21, 2007. View at Google Scholar · View at Scopus
  26. D. Meressa, R. M. Hurtado, J. R. Andrews et al., “Achieving high treatment success for multidrug-resistant TB in Africa: initiation and scale-up of MDR TB care in Ethiopia—an observational cohort study,” Thorax, vol. 70, no. 12, pp. 1181–1188, 2015. View at Publisher · View at Google Scholar
  27. L. Anderson, S. Tamne, J. Watson et al., “Treatment outcome of multi-drug resistant tuberculosis in the United Kingdom: retrospective-prospective cohort study from 2004 to 2007,” Eurosurveillance, vol. 18, no. 40, pp. 1–10, 2013. View at Publisher · View at Google Scholar
  28. V. Milanov, D. Falzon, M. Zamfirova et al., “Factors associated with treatment success and death in cases with multidrug-resistant tuberculosis in Bulgaria, 2009–2010,” International Journal of Mycobacteriology, vol. 4, no. 2, pp. 131–137, 2015, 2014 Asian African Society for Mycobacteriology. Production and hosting by Elsevier Ltd. All rights reserved. View at Publisher · View at Google Scholar
  29. E. W. Mollel and J. O. Chilongola, “Predictors for mortality among multidrug-resistant tuberculosis patients in tanzania,” Journal of Tropical Medicine, vol. 2017, Article ID 9241238, 6 pages, 2017. View at Google Scholar · View at Scopus
  30. N. R. Gandhi, J. R. Andrews, J. C. M. Brust et al., “Risk factors for mortality among MDR- and XDR-TB patients in a high HIV prevalence setting,” The International Journal of Tuberculosis and Lung Disease, vol. 16, no. 1, pp. 90–97, 2012. View at Publisher · View at Google Scholar · View at Scopus
  31. K. Chung-Delgado, S. Guillen-Bravo, A. Revilla-Montag, and A. Bernabe-Ortiz, “Mortality among MDR-TB cases: comparison with drug-susceptible tuberculosis and associated factors,” PLoS ONE, vol. 10, no. 3, Article ID e0119332, pp. 1–10, 2015. View at Publisher · View at Google Scholar · View at Scopus
  32. M. A. Gadallah, A. Mokhtar, M. Rady, E. El-Moghazy, M. Fawzy, and S. K. Kandil, “Prognostic factors of treatment among patients with multidrug-resistant tuberculosis in Egypt,” Journal of the Formosan Medical Association, vol. 115, no. 11, pp. 997–1003, 2016. View at Publisher · View at Google Scholar
  33. A. D. Salindri, M. Kipiani, R. R. Kempker et al., “Diabetes reduces the rate of sputum culture conversion in patients with newly diagnosed multidrug-resistant tuberculosis,” Open Forum Infectious Diseases, vol. 3, no. 3, pp. 1–10, 2016. View at Publisher · View at Google Scholar
  34. Y. A. Kang, S. Y. Kim, K. Jo et al., “Impact of diabetes on treatment outcomes and long-term survival in multidrug-resistant tuberculosis,” Respiration, vol. 86, no. 6, pp. 472–478, 2013. View at Publisher · View at Google Scholar