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| Research activity code (description) and subcategory |
|
| (1) Underpinning research (research that underpins investigations into the cause, development, detection, treatment, and management of diseases, conditions, and ill health) |
| (1.1) Normal biological development and functioning |
| (1.2) Psychological and socio-economic processes |
| (1.3) Chemical and physical sciences |
| (1.4) Methodologies and measurements |
| (1.5) Resources and infrastructure (underpinning) |
| (2) Aetiology (identification of determinants that are involved in the cause, risk, or development of disease, conditions, and ill health) |
| (2.1) Biological and endogenous factors |
| (2.2) Factors relating to the physical environment |
| (2.3) Psychological, social, and economic factors |
| (2.4) Surveillance and distribution |
| (2.5) Research design and methodologies (etiology) |
| (2.6) Resources and infrastructure (etiology) |
| (3) Prevention of disease and conditions and promotion of well-being (research aimed at the primary prevention of disease, conditions, or ill health or promotion of well-being) |
| (3.1) Primary prevention interventions to modify behaviors or promote well-being |
| (3.2) Interventions to alter physical and biological environmental risks |
| (3.3) Nutrition and chemoprevention |
| (3.4) Vaccines |
| (3.5) Resources and infrastructure (prevention) |
| (4) Detection, screening, and diagnosis (discovery, development, and evaluation of diagnostic, prognostic, and predictive markers and technologies) |
| (4.1) Discovery and preclinical testing of markers and technologies |
| (4.2) Evaluation of markers and technologies |
| (4.3) Influences and impact |
| (4.4) Population screening |
| (4.5) Resources and infrastructure (detection) |
| (5) Development of treatments and therapeutic interventions (discovery and development of therapeutic interventions and testing in model systems and preclinical settings) |
| (5.1) Pharmaceuticals |
| (5.2) Cellular and gene therapies |
| (5.3) Medical devices |
| (5.4) Surgery |
| (5.5) Radiotherapy and other noninvasive therapies |
| (5.6) Psychological and behavioral |
| (5.7) Physical |
| (5.8) Complementary |
| (5.9) Resources and infrastructure (development of treatments) |
| (6) Evaluation of treatments and therapeutic interventions (testing and evaluation of therapeutic interventions in a clinical, community, or applied settings) |
| (6.1) Pharmaceuticals |
| (6.2) Cellular and gene therapies |
| (6.3) Medical devices |
| (6.4) Surgery |
| (6.5) Radiotherapy and other noninvasive therapies |
| (6.6) Psychological and behavioral |
| (6.7) Physical |
| (6.8) Complementary |
| (6.9) Resources and infrastructure (evaluation of treatments) |
| (7) Management of diseases and conditions (research into individual care needs and management of disease, conditions, or ill health) |
| (7.1) Individual care needs |
| (7.2) End of life care |
| (7.3) Management and decision-making |
| (7.4) Resources and infrastructure (disease management) |
| (8) Health and social care service research (research into the provision and delivery of health and social care services, health policy, and studies of research design, measurements, and methodologies) |
| (8.1) Organization and delivery of services |
| (8.2) Health and welfare economics |
| (8.3) Policy, ethics, and research governance |
| (8.4) Research design and methodologies |
| (8.5) Resources and infrastructure (health services) |
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