The Scientific World Journal

The Scientific World Journal / 2001 / Article
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Collection of Directions in Science Articles from TheScientificWorldJOURNAL

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Directions in Science | Open Access

Volume 1 |Article ID 783986 | 2 pages | https://doi.org/10.1100/tsw.2001.30

Identification of a T1D Susceptibility Gene

Abstract

It is not known what causes type 1 diabetes (T1D), which affects over 1 million people in the U.S. alone. Each year, 30,000 young people in the U.S. develop this disease and depend on insulin injections thereafter. Because of the huge cost to the individual, the family, and to society in increased health care costs, it is important to find what makes these people susceptible. The disease process itself is clear: the individual’s immune system — T lymphocytes in particular — attack and destroy the body’s insulin-producing cells. But how and why this autoimmune process starts or proceeds unregulated is still not known.


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