The Scientific World Journal

The Scientific World Journal / 2002 / Article
Special Issue

Reviews in Stem and Progenitor Cells

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Review Article | Open Access

Volume 2 |Article ID 513154 | 11 pages |

Formation of Neural Precursor Cell Populations by Differentiation of Embryonic Stem Cells In Vitro

Received15 Oct 2001
Revised20 Dec 2001
Accepted15 Jan 2002


Recent interest in the generation of neural lineages by differentiation of embryonic stem cells arises from the opportunities represented by a developmentally normal, unlimited source of material that can be manipulated genetically with precision. Several experimental approaches, which differ conceptually, in the route of differentiation and the characteristics of the resulting cell population have been reported. In this review we undertake a comparative analysis of these approaches and their suitability for experimental investigation or implantation.

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