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TheScientificWorldJOURNAL
Volume 8, Pages 1325-1327
http://dx.doi.org/10.1100/tsw.2008.164
Directions in Science

Inhibition of Steroid Sulfatase Activity in Endometriotic Implants by STX64 (667Coumate): A Potential New Therapy

1Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK
2Endocrinology and Metabolic Medicine and Sterix Ltd., Imperial College London, St. Mary's Hospital, Praed Street, London,W2 1NY, UK
3Medicinal Chemistry, Department of Pharmacy and Pharmacology and Sterix Ltd., University of Bath, Claverton Down, Bath, BA2 7AY, UK

Received 20 August 2008; Revised 10 December 2008; Accepted 17 December 2008

Academic Editor: Martin Goette

Copyright © 2008 L. Fusi et al.

Citations to this Article [7 citations]

The following is the list of published articles that have cited the current article.

  • René Maltais, and Donald Poirier, “Steroid sulfatase inhibitors: A review covering the promising 2000–2010 decade,” Steroids, vol. 76, no. 10-11, pp. 929–948, 2011. View at Publisher · View at Google Scholar
  • L. W. Lawrence Woo, Atul Purohit, and Barry V. L. Potter, “Development of steroid sulfatase inhibitors,” Molecular and Cellular Endocrinology, vol. 340, no. 2, pp. 175–185, 2011. View at Publisher · View at Google Scholar
  • Mark P. Thomas, and Barry V. L. Potter, “Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women’s Health,” Journal of Medicinal Chemistry, pp. 150520101659003, 2015. View at Publisher · View at Google Scholar
  • Mark P. Thomas, and Barry V.L. Potter, “Estrogen O-sulfamates and their analogues: Clinical steroid sulfatase inhibitors with broad potential,” The Journal of Steroid Biochemistry and Molecular Biology, 2015. View at Publisher · View at Google Scholar
  • Jonathan W. Mueller, Lorna C. Gilligan, Jan Idkowiak, Wiebke Arlt, and Paul A. Foster, “The Regulation of Steroid Action by Sulfation and Desulfation,” Endocrine Reviews, vol. 36, no. 5, pp. 526–563, 2015. View at Publisher · View at Google Scholar
  • Sangyun Shin, Hee-Jung Im, Dong-Jin Ye, Hyoung-Seok Baek, Donghak Kim, Young-Jin Chun, Yeo-Jung Kwon, and Hyung-Kyoon Choi, “Human steroid sulfatase induces Wnt/β-catenin signaling and epithelial-mesenchymal transition by upregulating Twist1 and HIF-1α in human prostate and cervical cancer cells,” Oncotarget, vol. 8, no. 37, pp. 61604–61617, 2017. View at Publisher · View at Google Scholar
  • Carla A Piccinato, Helena Malvezzi, Douglas A Gibson, and Philippa T K Saunders, “SULFATION PATHWAYS: Contribution of intracrine oestrogens to the aetiology of endometriosis,” Journal of Molecular Endocrinology, vol. 61, no. 2, pp. T253–T270, 2018. View at Publisher · View at Google Scholar