Table of Contents Author Guidelines Submit a Manuscript
TheScientificWorldJOURNAL
Volume 8, Pages 720-751
http://dx.doi.org/10.1100/tsw.2008.99
Review

Synthesis and Biological Aspects of Mycolic Acids: An Important Target Against Mycobacterium tuberculosis

1Instituto de Tecnologia em Fármacos-Far-Manguinhos, Rua Sizenando Nabuco, 100, Manguinhos, 21041-250 Rio de Janeiro, RJ, Brazil
2Instituto de Química Universidade Federal Fluminense, Campus do Valonguinho S/n Centro 24020-150 Niterói, RJ, Brazil
3Instituto de Química, Universidade Federal do Rio de Janeiro, 21941-590 Rio de Janeiro, RJ, Brazil
4Departamento de Química, Universidade Federal de Juiz de Fora, 36036-330 Juiz de Fora, MG, Brazil

Received 4 April 2008; Accepted 10 July 2008

Academic Editor: Frank S. Walsh

Copyright © 2008 Marcus Vinícius Nora de Souza et al.

Citations to this Article [23 citations]

The following is the list of published articles that have cited the current article.

  • Fatima M. F. Vergara, Maria das G. M. O. Henriques, Andre L. P. Candea, Jim L. Wardell, and Marcus V. N. De Souza, “Antitubercular activity of alpha,omega-diaminoalkanes, H2N(CH2)(n)NH2,” Bioorganic & Medicinal Chemistry Letters, vol. 19, no. 17, pp. 4937–4938, 2009. View at Publisher · View at Google Scholar
  • Anshika Sharma, Gopal K. Khuller, and Sadhna Sharma, “Peptide deformylase - a promising therapeutic target for tuberculosis and antibacterial drug discovery,” Expert Opinion On Therapeutic Targets, vol. 13, no. 7, pp. 753–765, 2009. View at Publisher · View at Google Scholar
  • Marcus Vinícius Nora de Souza, “Promising candidates in clinical trials against multidrug-resistant tuberculosis (MDR-TB) based on natural products,” Fitoterapia, vol. 80, no. 8, pp. 453–460, 2009. View at Publisher · View at Google Scholar
  • Marcelle de L. Ferreira, Thatyana R. A. Vasconcelos, Erika M. de Carvalho, Maria C. S. Lourenco, Solange M. S. V. Wardell, James L. Wardell, Vitor F. Ferreira, and Marcus V. N. de Souza, “Synthesis and antitubercular activity of novel Schiff bases derived from D-mannitol,” Carbohydrate Research, vol. 344, no. 15, pp. 2042–2047, 2009. View at Publisher · View at Google Scholar
  • Mauro V. de Almeida, Felipe R. C. Vicente, Maria Cristina S. Lourenco, Joao Vitor de Assis, Silvia H. Cardoso, and Marcus V. N. de Souza, “Synthesis And Antitubercular Activity Of Isoniazid Condensed With Carbohydrate Derivatives,” Quimica Nova, vol. 32, no. 6, pp. 1557–1560, 2009. View at Publisher · View at Google Scholar
  • Mauricio F. Saraiva, Marcus V. N. de Souza, Marie E. Tran Huu Dau, Debora P. Araujo, Gustavo S. G. de Carvalho, and Mauro V. de Almeida, “Synthesis and antitubercular evaluation of new fluoroquinolone derivatives coupled with carbohydrates,” Carbohydrate Research, vol. 345, no. 6, pp. 761–767, 2010. View at Publisher · View at Google Scholar
  • Raoni S.B. Gonçalves, Carlos R. Kaiser, Maria C.S. Loureno, Marcus V.N. De Souza, James L. Wardell, Solange M.S.V. Wardell, and Adilson D. Da Silva, “Synthesis and antitubercular activity of new mefloquine-oxazolidine derivatives,” European Journal of Medicinal Chemistry, vol. 45, no. 12, pp. 6095–6100, 2010. View at Publisher · View at Google Scholar
  • Marcelle de L. Ferreira, Raoni S. B. Goncalves, Laura N. de F. Cardoso, Carlos R. Kaiser, Andre L. P. Candea, Maria das Gracas M. de O. Henriques, Maria C. S. Lourenco, Flavio A. F. M. Bezerra, and Marcus V. N. de Souza, “Synthesis and Antitubercular Activity of Heteroaromatic Isonicotinoyl and 7-Chloro-4-Quinolinyl Hydrazone Derivatives,” Thescientificworldjournal, vol. 10, pp. 1347–1355, 2010. View at Publisher · View at Google Scholar
  • Alexandre Cuin, Antonio Carlos Massabni, Guilherme Alves Pereira, Clarice Queico Fujimura Leite, Fernando Rogério Pavan, Renata Sesti-Costa, Tassiele Andréa Heinrich, and Claudio M. Costa-Neto, “6-Mercaptopurine complexes with silver and gold ions: Anti-tuberculosis and anti-cancer activities,” Biomedicine and Pharmacotherapy, vol. 65, no. 5, pp. 334–338, 2011. View at Publisher · View at Google Scholar
  • Andre Luis Peixoto Candea, Alessandra Campbell Pinheiro, Thais Cristina Mendonca Nogueira, Marcus Vinicius Nora de Souza, Samir Aquino Carvalho, Edson Ferreira da Silva, Maria Cristina Silva Lourenco, Larisse de Oliveira Feitosa, Carlos Roland Kaiser, and Maria das Gracas Mueller de Oliveira Henriques, “Synthesis and Antitubercular Activity of New L-serinyl Hydrazone Derivatives,” Medicinal Chemistry, vol. 7, no. 6, pp. 611–623, 2011. View at Publisher · View at Google Scholar
  • Adriana F. Faria, Luiza F. Marcellos, Juliana P. Vasconcelos, Marcus V. N. De Souza, Antonio L. S. Júnior, Weberton R. Do Carmo, Renata Diniz, and Marcone A. L. De Oliveira, “Ethambutol analysis by copper complexation in pharmaceutical formulations: Spectrophotometry and crystal structure,” Journal of the Brazilian Chemical Society, vol. 22, no. 5, pp. 867–874, 2011. View at Publisher · View at Google Scholar
  • Adriana F. Faria, Juliana P. Vasconcelos, Raoni S. B. Gonçalves, Marcus V. N. Souza, and Marcone A. L. Oliveira, “Simultaneous Analysis of Isoniazid and Its Impurities by CZE,” Chromatographia, vol. 75, no. 21-22, pp. 1335–1339, 2012. View at Publisher · View at Google Scholar
  • Luiza F. Marcellos, Adriana F. Faria, Marcus V. N. Souza, Mariana R. Almeida, Guilherme P. Sabin, Ronei J. Poppi, and Marcone A. L. Oliveira, “Simultaneous analysis of first-line anti-tuberculosis drugs in tablets by UV spectrophotometry compared to capillary zone electrophoresis,” Central European Journal of Chemistry, vol. 10, no. 6, pp. 1808–1816, 2012. View at Publisher · View at Google Scholar
  • Avinash Sonawane, Soumitra Mohanty, Lakshmanan Jagannathan, Ashley Bekolay, and Sulagna Banerjee, “ Role of glycans and glycoproteins in disease development by Mycobacterium tuberculosis ,” Critical Reviews in Microbiology, vol. 38, no. 3, pp. 250–266, 2012. View at Publisher · View at Google Scholar
  • Cristiane F. Da Costa, Alessandra C. Pinheiro, Mauro V. De Almeida, Maria C.S. Lourenço, and Marcus V.N. De Souza, “Synthesis and Antitubercular Activity of Novel Amino Acid Derivatives,” Chemical Biology and Drug Design, vol. 79, no. 2, pp. 216–222, 2012. View at Publisher · View at Google Scholar
  • Monika Jankute, Shipra Grover, Amrita K Rana, and Gurdyal S Besra, “Arabinogalactan and lipoarabinomannan biosynthesis: structure, biogenesis and their potential as drug targets,” Future Microbiology, vol. 7, no. 1, pp. 129–147, 2012. View at Publisher · View at Google Scholar
  • Tatiane S. Coelho, Jessica B. Cantos, Marcelle L.F. Bispo, Raoni S.B. Gonçalves, Camilo H.S. Lima, Pedro E.A. da Silva, and Marcus V.N. Souza, “In vitro anti-mycobacterial activity of (E)-N'-(monosubstituted-benzylidene) isonicotinohydrazide derivatives against isoniazidresistant strains,” Infectious Disease Reports, vol. 4, no. 1, pp. 49–51, 2012. View at Publisher · View at Google Scholar
  • Steven Halouska, Robert J. Fenton, Denise K. Zinniel, Darrell D. Marshall, Raúl G. Barletta, and Robert Powers, “ Metabolomics Analysis Identifies d -Alanine- d -Alanine Ligase as the Primary Lethal Target of d -Cycloserine in Mycobacteria ,” Journal of Proteome Research, vol. 13, no. 2, pp. 1065–1076, 2014. View at Publisher · View at Google Scholar
  • Felipe A. R. Rodrigues, Augusto C. A. Oliveira, Bruno C. Cavalcanti, Claudia Pessoa, Alessandra C. Pinheiro, and Marcus V. N. De Souza, “Biological evaluation of isoniazid derivatives as an anticancer class,” Scientia Pharmaceutica, vol. 82, no. 1, pp. 21–28, 2014. View at Publisher · View at Google Scholar
  • G. Jiménez-Galisteo, T. G. Villa, T. Vinuesa, M. Viñas, A. Domínguez, and E. Muñoz, “ Draft Genome Sequence of the Bacterium Gordonia jacobaea , a New Member of the Gordonia Genus ,” Genome Announcements, vol. 3, no. 5, pp. e00995-15, 2015. View at Publisher · View at Google Scholar
  • Eunice A. Nyawade, Holger B. Friedrich, BernardOmondi, Hafizah Y. Chenia, Moganavelli Singh, and Sridevi Gorle, “Synthesis and characterization of new α,αʹ-diaminoalkane-bridged dicarbonyl(η5-cyclopentadienyl)ruthenium(II) complex salts: Antibacterial activity tests of η5-cyclopentadienyl dicarbonyl ruthenium(II) amine complexes,” Journal of Organometallic Chemistry, 2015. View at Publisher · View at Google Scholar
  • Veena C. Yeruva, Mamata Savanagouder, Radhika Khandelwal, Apoorva Kulkarni, Yogendra Sharma, and Tirumalai R. Raghunand, “The Mycobacterium tuberculosis desaturase DesA1 (Rv0824c) is a Ca2+ binding protein,” Biochemical and Biophysical Research Communications, vol. 480, no. 1, pp. 29–35, 2016. View at Publisher · View at Google Scholar
  • A. H. S. Kartamihardja, Y. Kurniawati, and R. Gunawan, “Diagnostic value of 99mTc-ethambutol scintigraphy in tuberculosis: compared to microbiological and histopathological tests,” Annals of Nuclear Medicine, 2017. View at Publisher · View at Google Scholar