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Volume 9 (2009), Pages 920-923
Case Study

Simultaneous Penile and Signet Ring Cell Bladder Carcinoma in Renal Transplant Recipient: A First Case

1Department of Surgery, Section of Urology, University of Pisa, Italy
2Department of Surgery, Division of Anatomic Pathology, University of Pisa, Italy
3Division of Surgery in Uremic and Diabetic Patient, University of Pisa, Italy

Received 31 May 2009; Revised 26 August 2009; Accepted 30 August 2009

Academic Editor: Anthony Atala

Copyright © 2009 Francesca Manassero et al.


The incidence and prevalence of cancer increase with time after transplantation. Therefore, a risk-adapted screening process is very important in order to identify low-grade malignancies early in their development. This provides the opportunity to initiate appropriate immunosuppressive regimens depending on the tumor type and stage of development. The first case presented is one of a 65-year-old patient with a double genitourinary carcinoma (penis and bladder). The patient received kidney transplantation 7 years prior to this event. After adequate surgical treatment (partial amputation of the penis for squamous cell carcinoma and complete transurethral resection of bladder adenocarcinoma), the patient was noted to be free of tumor recurrence and had functioning renal graft with a 2-year follow-up.