Table of Contents Author Guidelines Submit a Manuscript
TheScientificWorldJOURNAL
Volume 10 (2010), Pages 624-632
http://dx.doi.org/10.1100/tsw.2010.58
Mini-Review Article

Recent Insights into the Implication of Nitric Oxide in Osteoblast Differentiation and Proliferation during Bone Development

1Departamento de Fisiologia, Facultad de Medicina, Universidad de Alcala, Madrid, Spain
2Fundación Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain

Received 31 December 2009; Revised 3 March 2010; Accepted 10 March 2010

Academic Editor: Martin Goette

Copyright © 2010 Marta Saura et al.

Citations to this Article [32 citations]

The following is the list of published articles that have cited the current article.

  • M. V. Thomas, and D. A. Puleo, “Infection, Inflammation, and Bone Regeneration: a Paradoxical Relationship,” Journal of Dental Research, vol. 90, no. 9, pp. 1052–1061, 2011. View at Publisher · View at Google Scholar
  • Marzia Leidi, Federica Dellera, Massimo Mariotti, and Jeanette A. M. Maier, “High magnesium inhibits human osteoblast differentiation in vitro,” Magnesium Research, vol. 24, no. 1, pp. 1–6, 2011. View at Publisher · View at Google Scholar
  • Vikas Saini, and Susan McCormick, “Changes in NO, iNOS and eNOS Expression in MLO-Y4 Cells After Low-intensity Pulsed Ultrasound Treatment With or Without Shear Stress Exposure,” Cellular And Molecular Bioengineering, vol. 4, no. 1, pp. 91–105, 2011. View at Publisher · View at Google Scholar
  • Guozheng Cheng, Yuankun Zhai, Keming Chen, Jian Zhou, Guiqiu Han, Ruiqing Zhu, Leiguo Ming, Peng Song, and Jiaqi Wang, “Sinusoidal electromagnetic field stimulates rat osteoblast differentiation and maturation via activation of NO-cGMP-PKG pathway,” Nitric Oxide-Biology And Chemistry, vol. 25, no. 3, pp. 316–325, 2011. View at Publisher · View at Google Scholar
  • Wei Huang, Wei-lin Shang, Hua-dong Wang, Wen-wen Wu, and Shu-xun Hou, “Sirt1 overexpression protects murine osteoblasts against TNF-α-induced injury in vitro by suppressing the NF-κB signaling pathway,” Acta Pharmacologica Sinica, vol. 33, no. 5, pp. 668–674, 2012. View at Publisher · View at Google Scholar
  • S. Pilz, A. Meinitzer, A. Tomaschitz, K. Kienreich, H. Dobnig, M. Schwarz, D. Wagner, C. Drechsler, C. Piswanger-Sölkner, W. März, and A. Fahrleitner-Pammer, “Associations of homoarginine with bone metabolism and density, muscle strength and mortality: cross-sectional and prospective data from 506 female nursing home patients,” Osteoporosis International, vol. 24, no. 1, pp. 377–381, 2012. View at Publisher · View at Google Scholar
  • Yongxin Ren, Lipeng Yu, Jin Fan, Ze Rui, Zhengzhe Hua, Zitao Zhang, Ning Zhang, and Guoyong Yin, “Phosphorylation of GIT1 tyrosine 321 is required for association with FAK at focal adhesions and for PDGF-activated migration of osteoblasts,” Molecular and Cellular Biochemistry, vol. 365, no. 1-2, pp. 109–118, 2012. View at Publisher · View at Google Scholar
  • Jose M. Moran, Raul Roncero-Martin, Francisco J. Rodriguez-Velasco, Julian F. Calderon-Garcia, Purificacion Rey-Sanchez, Vicente Vera, Maria L. Canal-Macias, and Juan D. Pedrera-Zamorano, “Effects of Curcumin on the Proliferation and Mineralization of Human Osteoblast-Like Cells: Implications of Nitric Oxide,” International Journal Of Molecular Sciences, vol. 13, no. 12, pp. 16104–16118, 2012. View at Publisher · View at Google Scholar
  • M.J. Holder, M.R. Milward, W.M. Palin, M.A. Hadis, and P.R. Cooper, “Effects of red light-emitting diode irradiation on dental pulp cells,” Journal of Dental Research, vol. 91, no. 10, pp. 961–966, 2012. View at Publisher · View at Google Scholar
  • Marzia Leidi, Federica Dellera, Massimo Mariotti, Giuseppe Banfi, Calogero Crapanzano, Walter Albisetti, and Jeanette A.M. Maier, “Nitric oxide mediates low magnesium inhibition of osteoblast-like cell proliferation,” The Journal of Nutritional Biochemistry, vol. 23, no. 10, pp. 1224–1229, 2012. View at Publisher · View at Google Scholar
  • Susanna P. Garamszegi, and Nandor Garamszegi, “Crosstalk signalling role in modulation of drugs side effects,” Current Molecular Pharmacology, vol. 5, no. 3, pp. 327–339, 2012. View at Publisher · View at Google Scholar
  • Debra A. Mayes, Tilat A. Rizvi, Haley Titus-Mitchell, Rachel Oberst, Georgianne M. Ciraolo, Charles V. Vorhees, Andrew P. Robinson, Stephen D. Miller, Jose A. Cancelas, Anat O. Stemmer-Rachamimov, and Nancy Ratner, “Nf1 Loss and Ras Hyperactivation in Oligodendrocytes Induce NOS-Driven Defects in Myelin and Vasculature,” Cell Reports, 2013. View at Publisher · View at Google Scholar
  • Martin L. Pall, “ Electromagnetic fields act via activation of voltage-gated calcium channels to produce beneficial or adverse effects ,” Journal of Cellular and Molecular Medicine, 2013. View at Publisher · View at Google Scholar
  • Marina A. Aleksinskaya, Ernst E. H. van Faassen, Jelly Nelissen, Ben J. A. Janssen, Jo G. R. de Mey, Roeland Hanemaaijer, Ton Rabelink, and Anton Jan van Zonneveld, “Identification of Free Nitric Oxide Radicals in Rat Bone Marrow: Implications for Progenitor Cell Mobilization in Hypertension,” PLoS ONE, vol. 8, no. 3, 2013. View at Publisher · View at Google Scholar
  • Denise Cazzato, Emma Assi, Claudia Moscheni, Silvia Brunelli, Clara De Palma, Davide Cervia, Cristiana Perrotta, and Emilio Clementi, “Nitric Oxide drives embryonic myogenesis in chicken through the upregulation of myogenic differentiation factors,” Experimental Cell Research, 2013. View at Publisher · View at Google Scholar
  • Yuan-Kun Zhai, Xiao-Yu Guo, Bao-Feng Ge, Ping Zhen, Xiao-Ni Ma, Jian Zhou, Hui-Ping Ma, Cory J. Xian, and Ke-Ming Chen, “Icariin stimulates the osteogenic differentiation of rat bone marrow stromal cells via activating the PI3K-AKT-eNOS-NO-cGMP-PKG,” Bone, vol. 66, pp. 189–198, 2014. View at Publisher · View at Google Scholar
  • J. Renn, B. Pruvot, and M. Muller, “Detection of nitric oxide by diaminofluorescein visualizes the skeleton in living zebrafish,” Journal of Applied Ichthyology, vol. 30, no. 4, pp. 701–706, 2014. View at Publisher · View at Google Scholar
  • Orkun Topcu Ali, Ferda Alev Akalin, Kemal Burak Sahbazoglu, Nermin Yamalik, Kamer Kilinc, Erdem Karabulut, and Tolga Fikret Tözüm, “Nitrite and nitrate levels of gingival crevicular fluid and saliva in subjects with gingivitis and chronic periodontitis.,” Journal of oral & maxillofacial research, vol. 5, no. 2, 2014. View at Publisher · View at Google Scholar
  • Pan Ma, Bin Gu, Wei Xiong, Baosheng Tan, Wei Geng, Jun Li, and Hongchen Liu, “Glimepiride Promotes Osteogenic Differentiation in Rat Osteoblasts via the PI3K/Akt/eNOS Pathway in a High Glucose Microenvironment,” Plos One, vol. 9, no. 11, 2014. View at Publisher · View at Google Scholar
  • Milena R. Kaluderovic, Marija Mojic, Joachim P. Schreckenbach, Danijela Maksimovic-Ivanic, Hans-Ludwig Graf, and Sanja Mijatovic, “A Key Role of Autophagy in Osteoblast Differentiation on Titanium-Based Dental Implants,” Cells Tissues Organs, vol. 200, no. 3-4, pp. 265–277, 2014. View at Publisher · View at Google Scholar
  • Mostafa Elsaadany, Gayathri Subramanian, Halim Ayan, and Eda Yildirim-Ayan, “Exogenous nitric oxide (NO) generated by NO-plasma treatment modulates osteoprogenitor cells early differentiation,” Journal of Physics D: Applied Physics, vol. 48, no. 34, pp. 345401, 2015. View at Publisher · View at Google Scholar
  • Peili Du, Zhihua Li, Lili Du, Huili Zhang, Yanmei Zhou, Wen Sun, Xue Xiao, Yutian He, Bin Sun, Yanhong Yu, and Dunjin Chen, “The effects of PBDE-209 exposure during pregnancy on placental ET-1 and eNOS expression and the birth weight of offspring,” International Journal Of Developmental Neuroscience, vol. 43, pp. 86–91, 2015. View at Publisher · View at Google Scholar
  • Jessica Aceto, Rasoul Nourizadeh-Lillabadi, Raphael Maree, Nadia Dardenne, Nathalie Jeanray, Louis Wehenkel, Peter Alestrom, Jack J. W. A. van Loon, and Marc Muller, “Zebrafish Bone and General Physiology Are Differently Affected by Hormones or Changes in Gravity,” Plos One, vol. 10, no. 6, 2015. View at Publisher · View at Google Scholar
  • Thomas Windhausen, Steeve Squifflet, Jorg Renn, and Marc Muller, “BMP Signaling Regulates Bone Morphogenesis in Zebrafish through Promoting Osteoblast Function as Assessed by Their Nitric Oxide Production,” Molecules, vol. 20, no. 5, pp. 7586–7601, 2015. View at Publisher · View at Google Scholar
  • Csaba Hegedűs, Agnieszka Robaszkiewicz, Petra Lakatos, Éva Szabó, and László Virág, “Poly(ADP-ribose) in the bone: from oxidative stress signal to structural element,” Free Radical Biology and Medicine, 2015. View at Publisher · View at Google Scholar
  • Yukiko Maeda, Nicholas H Farina, Melissa M Matzelle, Paul J Fanning, Jane B Lian, and Ellen M Gravallese, “Synovium-Derived MicroRNAs Regulate Bone Pathways in Rheumatoid Arthritis,” Journal of Bone and Mineral Research, vol. 32, no. 3, pp. 461–472, 2016. View at Publisher · View at Google Scholar
  • Ewelina Zielinska, Cecylia Tukaj, Marek Witold Radomski, and Iwona Inkielewicz-Stepniak, “Molecular mechanism of silver nanoparticles-inducedhuman osteoblast cell death: Protective effect of inducible nitric oxide synthase inhibitor,” PLoS ONE, vol. 11, no. 10, 2016. View at Publisher · View at Google Scholar
  • Bo Shuai, Rui Zhu, Wei Xu, Yanran Wu, Yingying Luo, Shenlan Yang, Yanping Zhou, and Danfang Deng, “Role of the ER/NO/cGMP Signaling Pathway in the Promotion of Osteogenic Differentiation of Rat Bone Marrow Mesenchymal Stem Cells by Actaea racemosa Extract,” Evidence-based Complementary and Alternative Medicine, vol. 2016, 2016. View at Publisher · View at Google Scholar
  • Elisa Torre, “Molecular signaling mechanisms behind polyphenol-induced bone anabolism,” Phytochemistry Reviews, 2017. View at Publisher · View at Google Scholar
  • Sabrina B. Cepeda, Marisa J. Sandoval, María B. Rauschemberger, and Virginia L. Massheimer, “Beneficial role of the phytoestrogen Genistein on vascular calcification,” The Journal of Nutritional Biochemistry, 2017. View at Publisher · View at Google Scholar
  • Milena Kaluđerović, Tamara Krajnović, Danijela Maksimović-Ivanić, Hans-Ludwig Graf, and Sanja Mijatović, “Ti-SLActive and TiZr-SLActive Dental Implant Surfaces Promote Fast Osteoblast Differentiation,” Coatings, vol. 7, no. 7, pp. 102, 2017. View at Publisher · View at Google Scholar
  • Giuseppe Pezzotti, Elia Marin, Tetsuya Adachi, Alfredo Rondinella, Francesco Boschetto, Wenliang Zhu, Nobuhiko Sugano, Ryan M. Bock, Bryan McEntire, and Sonny B. Bal, “Bioactive silicon nitride: A new therapeutic material for osteoarthropathy,” Scientific Reports, vol. 7, pp. 44848, 2017. View at Publisher · View at Google Scholar