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TheScientificWorldJOURNAL
Volume 11, Pages 437-453
http://dx.doi.org/10.1100/tsw.2011.36
Review Article

Toll-Like Receptors, Their Ligands, and Atherosclerosis

1Clinical Pharmacology, William Harvey Research Institute, Charterhouse Square, London, UK
2Department of Medicine, Duke University Medical Center and Mandel Center for Hypertension and Atherosclerosis Research, Durham, NC, USA

Received 13 November 2010; Revised 3 January 2011; Accepted 7 January 2011

Academic Editor: Charles N. Serhan

Copyright © 2011 Conrad Hodgkinson and Shu Ye.

Citations to this Article [24 citations]

The following is the list of published articles that have cited the current article.

  • Giuseppe Lippi, Massimo Franchini, and Giovanni Targher, “Arterial thrombus formation in cardiovascular disease,” Nature Reviews Cardiology, vol. 8, no. 9, pp. 502–512, 2011. View at Publisher · View at Google Scholar
  • Dirk Lievens, and Philipp von Hundelshausen, “Platelets in atherosclerosis,” Thrombosis and Haemostasis, vol. 106, no. 5, pp. 827–838, 2011. View at Publisher · View at Google Scholar
  • Y. T. Konttinen, T. Sillat, G. Barreto, M. Ainola, and D. C. E. Nordström, “Editorial: Osteoarthritis as an autoinflammatory disease caused by chondrocyte-mediated inflammatory responses,” Arthritis & Rheumatism, vol. 64, no. 3, pp. 613–616, 2012. View at Publisher · View at Google Scholar
  • Lidio Gonçalves Lima-Neto, Rosario Dominguez Crespo Hirata, André Ducati Luchessi, Vivian Nogueira Silbiger, Marco Antonio Stephano, Marcelo Ferraz Sampaio, Dikran Armaganijan, and Mario Hiroyuki Hirata, “CD14 and IL6 polymorphisms are associated with a pro-atherogenic profile in young adults with acute myocardial infarction,” Journal of Thrombosis and Thrombolysis, 2012. View at Publisher · View at Google Scholar
  • Dirk Lievens, and Philipp von Hundelshausenpp. 393–440, 2012. View at Publisher · View at Google Scholar
  • Chie Hayashi, Frank C. Gibson III, James A. Hamilton, Caroline A. Genco, George Papadopoulos, Cynthia V. Gudino, Ellen O. Weinberg, Kenneth R. Barth, Andrés G. Madrigal, Yang Chen, Hua Ning, and Michael LaValley, “Protective role for TLR4 signaling in atherosclerosis progression as revealed by infection with a common oral pathogen,” Journal of Immunology, vol. 189, no. 7, pp. 3681–3688, 2012. View at Publisher · View at Google Scholar
  • Faezeh Moghimpour Bijani, Jesus G. Vallejo, and Nima Rezaei, “Toll-like Receptor Signaling Pathways in Cardiovascular Diseases: Challenges and Opportunities,” International Reviews of Immunology, vol. 31, no. 5, pp. 379–395, 2012. View at Publisher · View at Google Scholar
  • Yi-Tzu Lin, Amanda Verma, and Conrad P. Hodgkinson, “Toll-like receptors and human disease: Lessons from single nucleotide polymorphisms,” Current Genomics, vol. 13, no. 8, pp. 633–645, 2012. View at Publisher · View at Google Scholar
  • Benjamin Chidi Onyeagucha, Melania E. Mercado-Pimentel, Jennifer Hutchison, Erik K. Flemington, and Mark A. Nelson, “S100P/RAGE signaling regulates microRNA-155 expression via AP-1 activation in colon cancer,” Experimental Cell Research, 2013. View at Publisher · View at Google Scholar
  • Dirk Lievens, and Philipp von Hundelshausen, “Platelets as Therapeutic Targets of Atherosclerosis,” Atherosclerosis, pp. 393–440, 2013. View at Publisher · View at Google Scholar
  • E.H.A.M. Elsenberg, J.E.M. Sels, M.A. Hillaert, A.H. Schoneveld, N.A.M. van den Dungen, T.C. van Holten, M. Roest, J.W. Jukema, A.J. van Zonneveld, P.G. de Groot, N. Pijls, G. Pasterkamp, and I.E. Hoefer, “Increased cytokine response after toll-like receptor stimulation in patients with stable coronary artery disease,” Atherosclerosis, vol. 231, no. 2, pp. 346–351, 2013. View at Publisher · View at Google Scholar
  • Tarvo Sillat, Gonçalo Barreto, Paul Clarijs, Antti Soininen, Mari Ainola, Jukka Pajarinen, Matti Korhonen, Yrjö T Konttinen, Regina Sakalyte, Mika Hukkanen, Pekka Ylinen, and Dan C E Nordström, “Toll-like receptors in human chondrocytes and osteoarthritic cartilage,” Acta Orthopaedica, pp. 1–8, 2013. View at Publisher · View at Google Scholar
  • Shinji Satoh, Ryoko Yada, Hiroko Inoue, Soichiro Omura, Emiko Ejima, Takahiro Mori, Katsuhiko Takenaka, Natsumi Kawamura, Kotaro Numaguchi, Etsuo Mori, Akemi Asoh, Toshihiro Nakamura, and Koji Hiyamuta, “Toll-like receptor-4 is upregulated in plaque debris of patients with acute coronary syndrome more than Toll-like receptor-2,” Heart and Vessels, 2014. View at Publisher · View at Google Scholar
  • Constantina Nasopoulou, Haralabos C. Karantonis, Maria Detopoulou, Constantinos A. Demopoulos, and Ioannis Zabetakis, “Exploiting the anti-inflammatory properties of olive (Olea europaea) in the sustainable production of functional food and neutraceuticals,” Phytochemistry Reviews, 2014. View at Publisher · View at Google Scholar
  • Christian Roberts, “Atherosclerosis,” Diet, Exercise, and Chronic Disease, pp. 133–210, 2014. View at Publisher · View at Google Scholar
  • Sadeep Shrestha, Marguerite R. Irvin, Carl Grunfeld, and Donna K. Arnett, “HIV, Inflammation, and Calcium in Atherosclerosis,” Arteriosclerosis Thrombosis and Vascular Biology, vol. 34, no. 2, pp. 244–250, 2014. View at Publisher · View at Google Scholar
  • Ben Arpad Kappel, and Massimo Federici, “Can renin inhibition by Aliskiren prove itself in Atherosclerosis prevention?,” Atherosclerosis, 2014. View at Publisher · View at Google Scholar
  • Dominic De Nardo, “Toll-like receptors: Activation, signalling and transcriptional modulation,” Cytokine, 2015. View at Publisher · View at Google Scholar
  • Maiwand Ahmadsei, Dirk Lievens, Christian Weber, Philipp von Hundelshausen, and Norbert Gerdes, “Immune-mediated and lipid-mediated platelet function in atherosclerosis,” Current Opinion in Lipidology, vol. 26, no. 5, pp. 438–448, 2015. View at Publisher · View at Google Scholar
  • César Pacheco-Tena, and Susana Aideé González-Chávez, “The Danger Model Approach to the Pathogenesis of the Rheumatic Diseases,” Journal of Immunology Research, vol. 2015, pp. 1–23, 2015. View at Publisher · View at Google Scholar
  • Swati Sharma, Iti Garg, and Mohammad Z Ashraf, “TLR signalling and association of TLR polymorphism with cardiovascular diseases,” Vascular Pharmacology, vol. 87, pp. 30–37, 2016. View at Publisher · View at Google Scholar
  • Jenny Jongstra-Bilen, Cindy X. Zhang, Timothy Wisnicki, Mengyi K. Li, Samantha White-Alfred, Ragave Ilaalagan, Dario M. Ferri, Ashley Deonarain, Mark H. Wan, Sharon J. Hyduk, Carolyn L. Cummins, and Myron I. Cybulsky, “Oxidized Low-Density Lipoprotein Loading of Macrophages Downregulates TLR-Induced Proinflammatory Responses in a Gene-Specific and Temporal Manner through Transcriptional Control,” The Journal of Immunology, vol. 199, no. 6, pp. 2149–2157, 2017. View at Publisher · View at Google Scholar
  • Tomoko Kurita-Ochiai, Tomomi Hashizume-Takizawa, Ryoki Kobayashi, Ujjal K. Bhawal, Akira Hosono, Noriko Kinukawa, and Sumito Oguchi, “Porphyromonas gingivalis promotes low-density lipoprotein oxidation and atherosclerosis,” Journal of Oral Biosciences, vol. 59, no. 1, pp. 44–49, 2017. View at Publisher · View at Google Scholar
  • Conrad P. Hodgkinson, Richard E. Pratt, Imke Kirste, Sophie Dal-Pra, John P. Cooke, and Victor J. Dzau, “Cardiomyocyte Maturation Requires TLR3 Activated Nuclear Factor Kappa B,” Stem Cells, 2018. View at Publisher · View at Google Scholar