Review Article

[Retracted] A Showcase of Bench-to-Bedside Regenerative Medicine at the 2010 ASNTR

Table 2

Summary of Parkinson’s disease studies at the 2010 ASNTR meeting.

Disease pathologyModelsNeuroprotectionTransplantTreatments

Morphological EtcBBB
impairment [5, 6]
Rapid loss of
striatal DA
innervations
[25]
calcium [35]
Rotenone [3, 4]Uncoupling proteins
[13]
Cografts [33], tissue + calcium channel inhibitors [34], NPCs [36, 37], hMSCs [40] DA receptor
agonist [24], antidepressants [26],
DBS [2729]

Gene therapy 𝛼 -Synuclein
silencing [14],
pleiotrophin [15]
GDNF + NPCs [38],
GDNF + hUCB [39]

InflammationIncreased [8, 9, 11]
DA toxicity [12]
Reduced microglial
activation [10]
Allantoin [21] PPAR-
𝛾 [22]

Growth factorsFetal-antigen 1
overexpression in
striatum [16]
GDNF and
development [19]
CDNF [20]GDNF + tissue
grafts [17, 18]