Quercetin Protects Primary Human Osteoblasts Exposed to Cigarette Smoke through Activation of the Antioxidative Enzymes HO-1 and SOD-1

Figure 2

Quercetin reduces CSM-induced ROS production in primary human osteoblasts. (a) Pre-incubation of primary human osteoblasts (𝑁=3, 𝑛=4) with subtoxic concentrations of Quercetin (25, 50, 100 μM) reduces the formation of ROS after 15 min treatment with CSM (OD₃₂₀ = 0.8). (b) Similar results were observed during coincubation. ^∗∗∗𝑃<0.001 compared to untreated cells, ^∘∘∘𝑃<0.001 compared to CSM-treated cells.

(a)

(b)