Research Article

Simple Reversed-Phase HPLC Method with Spectrophotometric Detection for Measuring Acetaminophen-Protein Adducts in Rat Liver Samples

Figure 1

Recovery of APAP-Cys from spiked rat liver matrix protein dispersion by using different methods to isolate the APAP-protein adducts. Values are shown as the mean ± SD for three samples. All values were compared against those obtained for an aqueous solution of APAP-Cys, representing 100% recovery, and where * 𝑃 < 0 . 0 1 versus aqueous solution.
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