The Scientific World Journal / 2012 / Article / Tab 1

Research Article

In Vitro Synergistic Effect of Psidium guineense (Swartz) in Combination with Antimicrobial Agents against Methicillin-Resistant Staphylococcus aureus Strains

Table 1

MIC/MBC of the aqueous extract of Psidium guineense and antimicrobial agents against MRSA strains.

Staphylococcus aureusMIC/MBC (μg/mL)
AMCAMPCEFCIPGETMERAEResistance phenotype1

ATCC 259233.12/6.243.12/6.243.12/6.243.12/6.240.39/0.783.12/6.24250/500Control strain
LFBM 0125.0/50.0400/800400/80050.0/10012.5/25.025.0/50.0250/500AMC, CFO, CIP, GET
LFBM 056.25/12.5100/20025/50.03.12/6.243.12/6.2412.5/25.0250/500AMP, AZI, CFO, PEN
LFBM 083.12/6.24100/20012.5/25.03.12/6.243.12/6.246.25/12.5250/500AMP; AZI, CIP, CFO
LFBM 1612.5/25.025.0/50.012.5/25.03.12/6.243.12/6.246.25/12.5250/500AMP, AZI, CFO, PEN
LFBM 2650.0/100400/800400/80050.0/10025.0/50.025.0/50.0250/500AMC, AMP, CFO, CIP
LFBM 2825.0/50.0400/800100/20050.0/10025.0/50.012.5/25.0250/500AMC, CIP, CFO, GET
LFBM 2912.5/25.050.0/10025/50.03.12/6.243.12/6.2412.5/25.0500/1000AMC, AMP, CFO, PEN
LFBM 3012.5/25.0200/40012.5/25.050.0/1003.12/6.2412.5/25.0250/500AMC, AMP, CFO, CIP
LFBM 3112.5/25.0100/10012.5/25.050.0/1003.12/6.246.25/12.5250/500AMP, AZI, CFO; CIP;
LFBM 3212.5/25.0200/20012.5/25.050.0/1003.12/6.2412.5/25.0250/500AMP, CFO, CIP, PEN
LFBM 3312.5/25.0200/200200/20050.0/1003.12/6.2412.5/25.0250/500AMC, AMP, CFO, CIP

MIC: minimal inhibitory concentration; MBC: minimal bactericidal concentration; ATCC: American Type Culture Collection; LFBM: Laboratório de Fisiologia e Bioquímica de Microorganismos; AMC: amoxicillin/clavulanic acid; AMP: ampicillin; AZI: azithromycin; CFO: cefoxitin; CIP: ciprofloxacin; GET: gentamicin; PEN: penicillin; MER: meropenem; AE: aqueous extract of P. guineense.
1Resistance phenotype determined by the disk-diffusion method.