Research Article

Angiotensins Inhibit Cell Growth in GH3 Lactosomatotroph Pituitary Tumor Cell Culture: A Possible Involvement of the p44/42 and p38 MAPK Pathways

Figure 6

The influence of p44/42 MAPK inhibitor PD98059 at concentration 10−5 M on angiotensin-II-(AII-) and angiotensin-5–8-(A5-8-) induced decrease of the cellular viability in the lactosomatotroph GH3 cell culture. 𝑋 axis: absolute values of the optical density (OD), auxiliary axis (▲): OD in the particular groups expressed as the percentage of the optical density measured at 450 nm of unstimulated cells (control (C) = 100%). 𝑋 ± SEM; * 𝑃 < 0 . 0 5 versus C, ** 𝑃 < 0 . 0 5 versus AII.
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