The Effect of an Enamel Matrix Derivative (Emdogain) Combined with Bone Ceramic on Bone Formation in Mandibular Defects: A Histomorphometric and Immunohistochemical Study in the Canine

Table 2

OPN staining intensity in each experimental group.

Treatment group	Staining intensity	Interval			Total
		2 weeks	4 weeks	6 weeks
EMD/BC with membrane	−	0	0	0	0
	+	0	0	0	0
	++	1	2	1	4
	+++	1	0	1	2
EMD/BC without membrane	−	0	0	0	0
	+	1	1	1	3
	++	0	1	0	1
	+++	1	0	1	2
Membrane only	−	0	0	1	1
	+	1	1	0	2
	++	1	1	1	3
	+++	0	0	0	0
Control	−	0	0	0	0
	+	2	2	2	6
	++	0	0	0	0
	+++	0	0	0	0

Ratings for OPN expression: −: no expression, +: mild expression, ++: moderate expression, ++++: strong expression.